Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 3/20 | 0.42 |
| ▸ | TACR2 | P21452 | 2/20 | 0.42 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.42 |
| ▸ | UTS2R | Q9UKP6 | 10/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8589466 | 0.88 | TACR1 (0.46) | TACR1TACR2UTS2ROPRK1CYP3A4 | |
| SCHEMBL8589979 | 0.84 | UTS2R (0.45) | TACR1RIPK1UTS2ROPRK1CYP3A4 | |
| SCHEMBL8594647 | 0.82 | RIPK1 (0.41) | TACR1TACR2RIPK1UTS2ROPRK1 | |
| Hydrochloric Acid SCHEMBL8592856 | 0.77 | POLB (0.49) | TACR1TACR2DRD2SLC6A2SLC6A4 | |
| SCHEMBL8592988 | 0.76 | TACR1 (0.41) | TACR1TACR2DRD2DRD4OPRM1 | |
| Hydrochloric Acid SCHEMBL8592439 | 0.75 | TACR2 (0.42) | TACR1TACR2MEN1LMNADRD2 | |
| SCHEMBL8592989 | 0.73 | TACR2 (0.48) | TACR1TACR2DRD2DRD1DRD4 | |
| Hydrochloric Acid SCHEMBL8593239 | 0.73 | TACR2 (0.49) | TACR1TACR2UTS2RCYP3A4CYP2D6 | |
| SCHEMBL8589463 | 0.72 | TACR1 (0.42) | TACR1TACR2OPRK1OPRM1OPRD1 | |
| Hydrochloric Acid SCHEMBL8593273 | 0.71 | UTS2R (0.56) | UTS2ROPRK1CYP3A4CYP2D6MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5770735-A | Polycyclic amine compounds and their enantiomers, their method of preparation and pharmaceutical compositions in which they are present | ELF SANOFI (FR) | 1998-06-23 | — | — | US | disclosed |