Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 2/20 | 0.42 |
| ▸ | TACR2 | P21452 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 7/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 7/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 7/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 6/20 | 0.41 |
| ▸ | CNR2 | P34972 | 6/20 | 0.39 |
| ▸ | CNR1 | P21554 | 3/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8594647 | 0.89 | RIPK1 (0.41) | TACR1TACR2OPRM1OPRK1OPRL1 | |
| SCHEMBL8589466 | 0.81 | TACR1 (0.46) | TACR1TACR2OPRK1 | |
| Hydrochloric Acid SCHEMBL8592855 | 0.78 | POLB (0.43) | TACR1TACR2OPRM1OPRK1OPRL1 | |
| SCHEMBL8592986 | 0.77 | OPRM1 (0.44) | TACR2OPRM1OPRK1OPRL1OPRD1 | |
| Hydrochloric Acid SCHEMBL8592434 | 0.76 | OPRM1 (0.41) | TACR1TACR2OPRM1OPRK1OPRL1 | |
| SCHEMBL8593208 | 0.72 | UTS2R (0.39) | TACR1TACR2OPRM1OPRK1ABCG2 | |
| SCHEMBL8594648 | 0.72 | TACR1 (0.42) | TACR1TACR2OPRM1OPRK1OPRD1 | |
| SCHEMBL8589975 | 0.71 | RIPK1 (0.41) | TACR1 | |
| Hydrochloric Acid SCHEMBL8593270 | 0.71 | UTS2R (0.47) | TACR1OPRK1 | |
| Hydrochloric Acid SCHEMBL8593239 | 0.69 | TACR2 (0.49) | TACR1TACR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5770735-A | Polycyclic amine compounds and their enantiomers, their method of preparation and pharmaceutical compositions in which they are present | ELF SANOFI (FR) | 1998-06-23 | — | — | US | disclosed |