Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.40 |
| ▸ | PLG | P00747 | 1/20 | 0.39 |
| ▸ | PLAT | P00750 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.37 |
| ▸ | TAB1 | Q15750 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MMP12 | P39900 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8595477 | 1.00 | FAAH (0.41) | FAAHKMT2ASMN1; SMN2TAS1R3TAS1R1 | |
| SCHEMBL8595472 | 1.00 | FAAH (0.41) | FAAHKMT2ASMN1; SMN2TAS1R3TAS1R1 | |
| SCHEMBL19975270 | 0.91 | FAAH (0.47) | FAAHKMT2ATAS1R3TAS1R1ALDH1A1 | |
| SCHEMBL16054834 | 0.83 | LMNA (0.44) | KMT2ASMN1; SMN2PLGPLATLMNA | |
| SCHEMBL16054838 | 0.83 | LMNA (0.44) | KMT2ASMN1; SMN2PLGPLATLMNA | |
| SCHEMBL16054840 | 0.83 | LMNA (0.44) | KMT2ASMN1; SMN2PLGPLATLMNA | |
| SCHEMBL16054837 | 0.83 | LMNA (0.44) | KMT2ASMN1; SMN2PLGPLATLMNA | |
| SCHEMBL19975260 | 0.77 | TDP1 (0.45) | FAAHKMT2ASMN1; SMN2ALDH1A1MAP3K7 | |
| SCHEMBL8597575 | 0.77 | CNR2 (0.41) | KMT2ASMN1; SMN2PLGPLATLMNA | |
| SCHEMBL8597577 | 0.77 | CNR2 (0.41) | KMT2ASMN1; SMN2PLGPLATLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0585130-B1 | External preparation for skin containing a depigmentation agent | SHISEIDO CO LTD (JP) | 1998-01-28 | — | — | EP | disclosed |
| US-5690914-A | TRANEXAMIC ACID DERIVATIVES FOR DEPIGMENTATION | SHISEIDO CO., LTD (JP) | 1997-11-25 | — | — | US | disclosed |
| EP-0585130-A2 | External preparation for skin containing a depigmentation agent | SHISEIDO COMPANY LIMITED (JP) | 1994-03-02 | — | — | EP | disclosed |