Phosphine

Phosphine

SCHEMBL8595692

CCc1ccc(CCl)c(CC)c1CC.P

nearest known ligand 0.35

Full drug profile on Sugi Atlas →

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CTRC Q99895 1/20 0.35
GABRA1 P14867 4/20 0.32
GABRB2 P47870 4/20 0.32
ALDH1A1 P00352 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2494174 0.97 CTRC (0.37) CTRCGABRA1GABRB2ALDH1A1TSHR
Ammonia Solution, Strong SCHEMBL135221 0.95 CTRC (0.35) CTRCGABRA1GABRB2ALDH1A1TSHR
SCHEMBL6915878 0.93 CTRC (0.39) CTRCGABRA1GABRB2
SCHEMBL7705299 0.93 CTRC (0.39) CTRCGABRA1GABRB2
SCHEMBL6917622 0.92 CTRC (0.34) CTRCGABRA1GABRB2
SCHEMBL29619533 0.84 GABRA1 (0.41) CTRCGABRA1GABRB2ALDH1A1
SCHEMBL166573 0.84 GABRA1 (0.41) CTRCGABRA1GABRB2ALDH1A1
SCHEMBL27829682 0.83 GABRA1 (0.46) GABRA1GABRB2ALDH1A1TSHR
Ammonia Solution, Strong SCHEMBL17239637 0.81 GABRA1 (0.44) GABRA1GABRB2ALDH1A1TSHR
Ammonia Solution, Strong SCHEMBL27539208 0.81 GABRA1 (0.39) CTRCGABRA1GABRB2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104892521-B A kind of synthesis of alpha-amido acid compounds and purification process 河北威远生物化工有限公司 2018-04-24 CN claimed
CN-105037060-A Clean synthesis process of alpha-amino acid compounds HEBEI VEYONG BIO CHEM CO LTD 2015-11-11 CN claimed
CN-104892521-A Synthesis and purification method for alpha-amino acid compound HEBEI VEYONG BIO CHEM CO LTD 2015-09-09 CN claimed
EP-0309794-B1 No-post-cure method of curing polyacrylate polymers ZEON CHEMICALS INC (US) 1998-01-28 EP claimed
US-5008345-A Two-Part Curing System Containing A Metallic Acid Salt And An Ammonium Or Phosphonium Quaternary Salt ZEON CHEMICAL USA, INC. (US) 1991-04-16 US claimed
US-4931509-A EPOXY-CONTAINING MONOMER; EXCELLENT VULCANIZING WITH UREAS, QUATERNARY AMMONIUM AND PHOSPHONIUM SALTS AND POLYCARBOXYLIC ACIDS OR ANHYDRIDES NIPPON ZEON CO., LTD. (JP) 1990-06-05 US claimed
JP-62095315-A None JP disclosed
CN-104892521-B A kind of synthesis of alpha-amido acid compounds and purification process 河北威远生物化工有限公司 2018-04-24 CN disclosed
CN-105037060-A Clean synthesis process of alpha-amino acid compounds HEBEI VEYONG BIO CHEM CO LTD 2015-11-11 CN disclosed
CN-104892521-A Synthesis and purification method for alpha-amino acid compound HEBEI VEYONG BIO CHEM CO LTD 2015-09-09 CN disclosed
US-20140155526-A1 POLYIMIDE COMPOSITION VARNISH, FILM USING THE SAME, AND METHOD OF MANUFACTURING THE POLYIMIDE COMPOSITION VARNISH SAMSUNG DISPLAY CO., LTD. (KR) 2014-06-05 US disclosed
EP-0309794-B1 No-post-cure method of curing polyacrylate polymers ZEON CHEMICALS INC (US) 1998-01-28 EP disclosed
EP-0362459-B1 Polyacrylate polymers utilizing substituted urea retarder ZEON CHEMICALS USA INC (US) 1994-08-10 EP disclosed
US-5079304-A Curable ZEON CHEMICALS U.S.A., INC. (US) 1992-01-07 US disclosed
US-5008345-A Two-Part Curing System Containing A Metallic Acid Salt And An Ammonium Or Phosphonium Quaternary Salt ZEON CHEMICAL USA, INC. (US) 1991-04-16 US disclosed
US-4931509-A EPOXY-CONTAINING MONOMER; EXCELLENT VULCANIZING WITH UREAS, QUATERNARY AMMONIUM AND PHOSPHONIUM SALTS AND POLYCARBOXYLIC ACIDS OR ANHYDRIDES NIPPON ZEON CO., LTD. (JP) 1990-06-05 US disclosed
EP-0362459-A1 Polyacrylate polymers utilizing substituted urea retarder Zeon Chemicals USA, Inc. (US) 1990-04-11 EP disclosed
EP-0309794-A2 No-post-cure method of curing polyacrylate polymers Zeon Chemicals USA, Inc. (US) 1989-04-05 EP disclosed
EP-0257640-A2 Vulcanizable elastomer composition NIPPON ZEON CO., LTD. (JP) 1988-03-02 EP disclosed
JP-S6295315-A ONE-PACK TYPE CURABLE EPOXY RESIN COMPOSITION MITSUBISHI PETROCHEM CO LTD 1987-05-01 JP disclosed