Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.52 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.43 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.42 |
| ▸ | ACR | P10323 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28744517 | 0.81 | SMN1; SMN2 (0.46) | ESR1ESR2L3MBTL1KMT2ASMN1; SMN2 | |
| SCHEMBL5238691 | 0.76 | KDM4E (0.43) | ESR1ESR2L3MBTL1KMT2ASMN1; SMN2 | |
| SCHEMBL8593494 | 0.76 | PDPK1 (0.42) | L3MBTL1KMT2ASMN1; SMN2PARP1MAPT | |
| SCHEMBL8591739 | 0.75 | CLEC4M (0.42) | L3MBTL1KMT2ASMN1; SMN2PARP1MAPT | |
| SCHEMBL4590419 | 0.74 | PDPK1 (0.40) | L3MBTL1KMT2APARP1GAAKDM4E | |
| SCHEMBL9117853 | 0.72 | ALDH1A1 (0.55) | ESR1ESR2L3MBTL1KMT2ASMN1; SMN2 | |
| SCHEMBL311792 | 0.71 | KMT2A (0.62) | ESR1ESR2L3MBTL1KMT2ACA1 | |
| SCHEMBL21159215 | 0.70 | KMT2A (0.67) | ESR1ESR2L3MBTL1KMT2ASMN1; SMN2 | |
| SCHEMBL8594220 | 0.70 | CLEC4M (0.38) | KMT2AGAAKDM4EALDH1A1HPGD | |
| P-Anisic Acid SCHEMBL8595768 | 0.69 | PDPK1 (0.67) | KMT2ASMN1; SMN2PARP10CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998055115-A1 | CARBOXAMIDES USEFUL AS 5-HT1F AGONISTS | ELI LILLY AND COMPANY (US) | 1998-12-10 | — | — | WO | disclosed |