Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTR | Q99707 | 1/20 | 0.46 |
| ▸ | SCN1A | P35498 | 10/20 | 0.41 |
| ▸ | SCN5A | Q14524 | 10/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 10/20 | 0.41 |
| ▸ | PARP1 | P09874 | 3/20 | 0.39 |
| ▸ | PARP2 | Q9UGN5 | 3/20 | 0.39 |
| ▸ | NPY1R | P25929 | 1/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8485599 | 0.80 | MTR (0.38) | MTRSCN1ASCN5ASCN9APARP1 | |
| SCHEMBL8479247 | 0.75 | SCN1A (0.37) | MTRSCN1ASCN5ASCN9APARP1 | |
| SCHEMBL8485591 | 0.74 | NPY1R (0.41) | MTRSCN1ASCN5ASCN9APARP1 | |
| SCHEMBL8658094 | 0.74 | MTR (0.45) | MTRSCN1ASCN5ASCN9APARP1 | |
| SCHEMBL8487928 | 0.74 | SCN1A (0.36) | MTRSCN1ASCN5ASCN9APARP1 | |
| SCHEMBL8479611 | 0.72 | SCN1A (0.35) | MTRSCN1ASCN5ASCN9APARP1 | |
| SCHEMBL6186498 | 0.72 | MTR (0.51) | MTRSCN1ASCN5ASCN9APARP1 | |
| SCHEMBL8664326 | 0.72 | MTR (0.35) | MTRSCN1ASCN5ASCN9APARP1 | |
| SCHEMBL8485593 | 0.71 | NPY1R (0.40) | MTRSCN1ASCN5ASCN9ANPY1R | |
| SCHEMBL8502235 | 0.71 | AOC3 (0.32) | MTRSCN1ASCN5ASCN9APARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0886637-A1 | INHIBITORS OF MICROSOMAL TRIGLYCERIDE TRANSFER PROTEIN AND METHOD | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-12-30 | — | — | EP | claimed |
| EP-0886637-A4 | — | — | 1998-12-30 | — | — | EP | claimed |