Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 1/20 | 0.32 |
| ▸ | SCN1A | P35498 | 6/20 | 0.32 |
| ▸ | SCN5A | Q14524 | 6/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 6/20 | 0.32 |
| ▸ | MTR | Q99707 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
| ▸ | KDM5A | P29375 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8664326 | 0.94 | MTR (0.35) | AOC3SCN1ASCN5ASCN9AMTR | |
| SCHEMBL8503706 | 0.94 | SCN1A (0.31) | AOC3SCN1ASCN5ASCN9AMTR | |
| SCHEMBL8503796 | 0.93 | AOC3 (0.30) | AOC3SCN1ASCN5ASCN9A | |
| SCHEMBL8479247 | 0.92 | SCN1A (0.37) | AOC3SCN1ASCN5ASCN9AMTR | |
| SCHEMBL8664250 | 0.88 | SCN1A (0.34) | AOC3SCN1ASCN5ASCN9AMTR | |
| SCHEMBL8666702 | 0.87 | SCN1A (0.33) | AOC3SCN1ASCN5ASCN9AMTR | |
| SCHEMBL8487928 | 0.86 | SCN1A (0.36) | AOC3SCN1ASCN5ASCN9AMTR | |
| SCHEMBL8479611 | 0.85 | SCN1A (0.35) | AOC3SCN1ASCN5ASCN9AMTR | |
| SCHEMBL8501239 | 0.79 | NPSR1 (0.33) | GAANPSR1 | |
| SCHEMBL8503795 | 0.79 | OPRK1 (0.31) | NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5885983-A | ANTICHOLESTEROL AGENTS, ANTILIPOLYTIC AGENTS, ANTILIPEMIC AGENTS FOR TREATING HYPERLIPEMIA, ATHEROSCLEROSIS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-03-23 | — | — | US | disclosed |