Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | BCL9 | O00512 | 1/20 | 0.31 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6197215 | 0.89 | ADRA1A (0.36) | ADRA1ABCL9CTNNB1KMT2A | |
| SCHEMBL8337661 | 0.89 | ADRA1A (0.36) | ADRA1ABCL9CTNNB1KMT2A | |
| SCHEMBL6786377 | 0.81 | — | — | |
| SCHEMBL6782160 | 0.77 | ADRA1A (0.36) | ADRA1AKMT2A | |
| SCHEMBL6217186 | 0.71 | ADRA1A (0.37) | ADRA1AKMT2A | |
| SCHEMBL6646229 | 0.70 | ADRA1D (0.39) | ADRA1ABCL9CTNNB1KMT2A | |
| SCHEMBL6216267 | 0.69 | PDE1C (0.38) | — | |
| SCHEMBL6782795 | 0.68 | ADRA1A (0.36) | ADRA1AKMT2A | |
| SCHEMBL6715274 | 0.68 | BCL9 (0.35) | ADRA1ABCL9CTNNB1 | |
| SCHEMBL6715281 | 0.68 | BCL9 (0.35) | ADRA1ABCL9CTNNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0790826-A4 | DIHYDROPYRIMIDINES AND USES THEREOF | SYNAPTIC PHARMA CORP (US) | 1998-11-11 | — | — | EP | disclosed |
| EP-0790826-A1 | DIHYDROPYRIMIDINES AND USES THEREOF | SYNAPTIC PHARMACEUTICAL CORPORATION (US) | 1997-08-27 | — | — | EP | disclosed |