Malonic Acid

Malonic Acid

SCHEMBL8596083

C=CC.C=CC.O=C(O)CC(=O)O

nearest known ligand 0.60

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LDHA P00338 1/20 0.60
SRR Q9GZT4 1/20 0.60
ALOX15 P16050 2/20 0.46
HSD17B10 Q99714 1/20 0.46
FFAR3 O14843 2/20 0.39
LMNA P02545 2/20 0.39
TSHR P16473 4/20 0.38
KDM4E B2RXH2 1/20 0.38
ALDH1A1 P00352 4/20 0.37
CYP2D6 P10635 2/20 0.35
MAPK1 P28482 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
ABCC4 O15439 1/20 0.35
MAPT P10636 1/20 0.35
HDAC3 O15379 1/20 0.33
HDAC1 Q13547 1/20 0.33
HDAC2 Q92769 1/20 0.33
HDAC8 Q9BY41 1/20 0.33
SLC6A2 P23975 1/20 0.33
SLC6A4 P31645 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Malonic Acid SCHEMBL5070361 1.00 LDHA (0.60) LDHASRRALOX15HSD17B10FFAR3
Malonic Acid SCHEMBL29617884 0.87 LDHA (0.45) LDHASRRALOX15HSD17B10FFAR3
Acetoacetic Acid SCHEMBL23581266 0.85 KDM4E (0.44) LDHASRRALOX15HSD17B10FFAR3
Acetoacetic Acid SCHEMBL30758649 0.85 KDM4E (0.44) LDHASRRALOX15HSD17B10FFAR3
Malonic Acid SCHEMBL17985762 0.83 LDHA (0.64) LDHASRRALOX15HSD17B10FFAR3
Malonic Acid SCHEMBL27569564 0.83 LDHA (0.64) LDHASRRALOX15HSD17B10FFAR3
Malonic Acid SCHEMBL28077252 0.83 LDHA (0.64) LDHASRRALOX15HSD17B10FFAR3
Propionic Acid SCHEMBL11605241 0.80 FFAR3 (0.67) ALOX15HSD17B10FFAR3LMNATSHR
Glycolic Acid SCHEMBL11323378 0.80 LMNA (0.39) LDHASRRALOX15HSD17B10FFAR3
Succinic Acid SCHEMBL7194377 0.80 EGLN1 (0.60) FFAR3LMNATSHRKDM4ECYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-10095904-A None JP disclosed
CN-109313987-B Electrolytic solution for electrolytic capacitor and electrolytic capacitor 三洋化成工业株式会社 2021-06-29 CN disclosed
JP-H1095904-A MOLD MATERIAL AND MOLD MOTOR MATSUSHITA ELECTRIC IND CO LTD 1998-04-14 JP disclosed