Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 13/20 | 0.60 |
| ▸ | ESR2 | Q92731 | 13/20 | 0.60 |
| ▸ | CNR1 | P21554 | 1/20 | 0.57 |
| ▸ | CNR2 | P34972 | 1/20 | 0.57 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.55 |
| ▸ | NAPEPLD | Q6IQ20 | 1/20 | 0.55 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.54 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.53 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.53 |
| ▸ | TUBB | P07437 | 1/20 | 0.53 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.53 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.53 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.53 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.53 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.53 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.53 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.53 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.53 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.53 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11548759 | 0.95 | ESR1 (0.66) | ESR1ESR2CNR1CNR2ITGA4 | |
| SCHEMBL11555855 | 0.94 | ESR1 (0.68) | ESR1ESR2CNR1CNR2ITGA4 | |
| SCHEMBL8597235 | 0.90 | ESR1 (0.58) | ESR1ESR2CNR1CNR2TUBB4A | |
| SCHEMBL11552316 | 0.90 | ESR1 (0.61) | ESR1ESR2CNR1CNR2PAX8 | |
| SCHEMBL7626639 | 0.90 | ESR1 (0.67) | ESR1ESR2CNR1 | |
| SCHEMBL4652009 | 0.89 | CNR2 (0.75) | ESR1ESR2CNR1CNR2ITGA4 | |
| SCHEMBL8600465 | 0.88 | ESR1 (0.62) | ESR1ESR2CNR1CNR2TUBB4A | |
| SCHEMBL8599094 | 0.87 | ESR1 (0.58) | ESR1ESR2CNR1CNR2TUBB4A | |
| SCHEMBL11547336 | 0.87 | ESR1 (0.61) | ESR1ESR2CNR1CNR2TUBB4A | |
| SCHEMBL11550720 | 0.86 | CNR1 (0.67) | ESR1ESR2CNR1CNR2ITGA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641791-B1 | NOVEL BENZOTHIOPHENE DERIVATIVE | TEIKOKU HORMONE MFG CO LTD (JP) | 1998-01-28 | — | — | EP | disclosed |
| US-5472962-A | Antiestrogenic agents | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 1995-12-05 | — | — | US | disclosed |
| EP-0641791-A1 | NOVEL BENZOTHIOPHENE DERIVATIVE | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 1995-03-08 | — | — | EP | disclosed |