Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
| ▸ | EDNRB | P24530 | 1/20 | 0.31 |
| ▸ | EDNRA | P25101 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8595353 | 0.88 | CES2 (0.38) | CES2MAPTHCAR2 | |
| SCHEMBL8595908 | 0.86 | CES2 (0.44) | CES2MAPT | |
| SCHEMBL8599478 | 0.85 | CES2 (0.47) | CES2MAPT | |
| SCHEMBL8599725 | 0.85 | CES2 (0.47) | CES2MAPT | |
| SCHEMBL8595349 | 0.85 | CES2 (0.47) | CES2MAPT | |
| SCHEMBL8598285 | 0.85 | CES2 (0.47) | CES2MAPT | |
| SCHEMBL8598637 | 0.85 | CES2 (0.47) | CES2MAPT | |
| SCHEMBL8599800 | 0.83 | THRB (0.32) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| SCHEMBL8602282 | 0.82 | HCAR2 (0.34) | CHRM1TDP1CES2HCAR2 | |
| SCHEMBL24760204 | 0.80 | CES2 (0.31) | CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0592669-B1 | OPTICALLY ACTIVE TRIFLUOROLACTIC ACID DERIVATIVE AND LIQUID CRYSTAL COMPOSITION | CHISSO CORP (JP) | 1998-01-28 | — | — | EP | disclosed |
| US-5665270-A | Optically active trifluorolactic acid derivative and liquid crystal composition | CHISSO CORPORATION (JP) | 1997-09-09 | — | — | US | disclosed |
| EP-0592669-A1 | OPTICALLY ACTIVE TRIFLUOROLACTIC ACID DERIVATIVE AND LIQUID CRYSTAL COMPOSITION | CHISSO CORPORATION (JP) | 1994-04-20 | — | — | EP | disclosed |
| EP-0070635-B1 | BETA-SUBSTITUTED POLYFLUOROPROPIONATE SALTS AND DERIVATIVES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-03-30 | — | — | EP | disclosed |