Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG | P00747 | 1/20 | 0.39 |
| ▸ | PLAT | P00750 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | ARG1 | P05089 | 3/20 | 0.32 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.30 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.30 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | ARG2 | P78540 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8597461 | 0.87 | PLG (0.37) | PLGPLATLMNACYP2D6ARG1 | |
| SCHEMBL8598972 | 0.86 | PLG (0.36) | PLGPLATLMNACYP2D6ARG1 | |
| SCHEMBL8601006 | 0.84 | SLC7A5 (0.41) | PLGPLATLMNACYP2D6ARG1 | |
| SCHEMBL8599106 | 0.83 | DPP4 (0.37) | PLGPLATLMNAARG1 | |
| SCHEMBL8596987 | 0.82 | PLG (0.38) | PLGPLATLMNACYP2D6ARG1 | |
| SCHEMBL8597484 | 0.81 | PLG (0.37) | PLGPLATLMNACYP2D6ARG1 | |
| SCHEMBL8600966 | 0.81 | PTGS1 (0.37) | PLGPLATLMNACYP2D6ARG1 | |
| SCHEMBL8597733 | 0.80 | PLG (0.36) | PLGPLATLMNACYP2D6ARG1 | |
| SCHEMBL8596550 | 0.78 | LMNA (0.42) | PLGPLATLMNACYP2D6ARG1 | |
| SCHEMBL8598012 | 0.78 | LMNA (0.42) | PLGPLATLMNACYP2D6ARG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0585130-B1 | External preparation for skin containing a depigmentation agent | SHISEIDO CO LTD (JP) | 1998-01-28 | — | — | EP | disclosed |
| US-5690914-A | TRANEXAMIC ACID DERIVATIVES FOR DEPIGMENTATION | SHISEIDO CO., LTD (JP) | 1997-11-25 | — | — | US | disclosed |
| EP-0585130-A2 | External preparation for skin containing a depigmentation agent | SHISEIDO COMPANY LIMITED (JP) | 1994-03-02 | — | — | EP | disclosed |