SCHEMBL8599106

SCHEMBL8599106

CC[C@H](C)[C@H](N)C(=O)C1(C(=O)O)CCC(CN)CC1

nearest known ligand 0.37

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 16/20 0.37
DPP8 Q6V1X1 7/20 0.37
DPP9 Q86TI2 5/20 0.37
DPP7 Q9UHL4 5/20 0.37
ARG1 P05089 1/20 0.35
FAP Q12884 2/20 0.35
PLG P00747 1/20 0.34
PLAT P00750 1/20 0.34
LMNA P02545 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8597461 0.87 PLG (0.37) ARG1PLGPLATLMNA
SCHEMBL8598972 0.85 PLG (0.36) DPP4DPP7ARG1PLGPLAT
SCHEMBL8596278 0.83 PLG (0.39) ARG1PLGPLATLMNA
SCHEMBL8601006 0.78 SLC7A5 (0.41) DPP4DPP8DPP9DPP7ARG1
SCHEMBL8596987 0.76 PLG (0.38) ARG1PLGPLATLMNA
Hydrochloric Acid SCHEMBL8596533 0.75 DPP4 (0.34) DPP4DPP8DPP9DPP7FAP
SCHEMBL8597484 0.75 PLG (0.37) DPP4ARG1PLGPLATLMNA
SCHEMBL8600966 0.75 PTGS1 (0.37) ARG1PLGPLATLMNA
SCHEMBL8597733 0.74 PLG (0.36) ARG1PLGPLATLMNA
SCHEMBL8596550 0.72 LMNA (0.42) DPP4DPP8DPP9DPP7ARG1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0585130-B1 External preparation for skin containing a depigmentation agent SHISEIDO CO LTD (JP) 1998-01-28 EP disclosed
US-5690914-A TRANEXAMIC ACID DERIVATIVES FOR DEPIGMENTATION SHISEIDO CO., LTD (JP) 1997-11-25 US disclosed