Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.65 |
| ▸ | CA2 | P00918 | 4/20 | 0.65 |
| ▸ | CA12 | O43570 | 3/20 | 0.65 |
| ▸ | CA7 | P43166 | 3/20 | 0.65 |
| ▸ | CA9 | Q16790 | 3/20 | 0.65 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.65 |
| ▸ | ESR1 | P03372 | 1/20 | 0.65 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | MAOA | P21397 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | STS | P08842 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | AGXT | P21549 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10821032 | 0.85 | CA1 (0.69) | CA1CA2CA12CA7CA9 | |
| SCHEMBL7746905 | 0.84 | CA1 (0.79) | CA1CA2CA12CA7CA9 | |
| SCHEMBL10287538 | 0.84 | CA12 (0.67) | CA1CA2CA12CA7CA9 | |
| SCHEMBL14281812 | 0.84 | CA12 (0.67) | CA1CA2CA12CA7CA9 | |
| SCHEMBL12935737 | 0.83 | TSHR (0.69) | ESR1LMNACYP1A2CYP3A4SMN1; SMN2 | |
| SCHEMBL128190 | 0.83 | CA1 (0.70) | CA1CA2CA12CA7CA9 | |
| SCHEMBL87450 | 0.82 | CA1 (0.83) | CA1CA2CA12CA7CA9 | |
| SCHEMBL6665051 | 0.82 | CA12 (0.65) | CA1CA2CA12CA7CA9 | |
| SCHEMBL1520636 | 0.81 | LOXL2 (0.67) | CA1CA2CA12CA7CA9 | |
| SCHEMBL687664 | 0.81 | LOXL2 (0.67) | CA1CA2CA12CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5726314-A | ACETYLCHOLINESTERASE INHIBITORS AS NERVE AGENT ANTIDOTES | GEORGIA TECH RESEARCH CORP. (US) | 1998-03-10 | — | — | US | disclosed |
| US-5714615-A | ACETYLCHOLINESTERASE ENZYME INHIBITOR, STIMULATE NICOTINIC RECEPTORS IN CENTRAL NERVOUS SYSTEM | GEORGIA TECH RESEARCH CORPORATION (US) | 1998-02-03 | — | — | US | disclosed |
| WO-1995021822-A1 | PYRIDINIUM COMPOUNDS | GEORGIA TECH RESEARCH CORPORATION (US) | 1995-08-17 | — | — | WO | disclosed |
| US-5290942-A | Acetylcholinesterase inhibitors | GEORGIA TECH RESEARCH CORPORATION (US) | 1994-03-01 | — | — | US | disclosed |
| US-5206371-A | Acetylcholinesterase inhibitor | GEORGIA TECH RESEARCH CORPORATION (US) | 1993-04-27 | — | — | US | disclosed |
| US-5180831-A | Acetylcholinesterase Inhibitors | GEORGIA TECH RESEARCH CORPORATION (US) | 1993-01-19 | — | — | US | disclosed |
| EP-0361067-B1 | DISUBSTITUTED NAPHTHALINES, PREPARATION PROCESSES AND THEIR HERBICIDAL USE | BAYER AG (DE) | 1992-11-11 | — | — | EP | disclosed |
| US-5108489-A | HERBICIDAL DISUBSTITUTED NAPHTHALENES | BAYER AKTIENGESELLSCHAFT (DE) | 1992-04-28 | — | — | US | disclosed |
| EP-0470430-A1 | Process for the preparation of oxyguanidins | BAYER AG (DE) | 1992-02-12 | — | — | EP | disclosed |
| US-5086177-A | Chemical intermediate for herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 1992-02-04 | — | — | US | disclosed |
| US-4980469-A | Reacting isothiourea of nitrogen containing heterocycle with hydroxylamine derivative | BAYER AKTIENGESELLSCHAFT (DE) | 1990-12-25 | — | — | US | disclosed |
| EP-0361067-A1 | Disubstituted naphthalines, preparation processes and their herbicidal use | BAYER AG (DE) | 1990-04-04 | — | — | EP | disclosed |
| EP-0358018-A2 | Process for the preparation of oxyguanidines | BAYER AG (DE) | 1990-03-14 | — | — | EP | disclosed |
| US-4725304-A | HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1988-02-16 | — | — | US | disclosed |
| EP-0224078-A1 | Thienyl sulfonyl guanidine derivatives | BAYER AG (DE) | 1987-06-03 | — | — | EP | disclosed |
| EP-0173956-A1 | Sulfonyl-guanidinotriazine derivatives | BAYER AG (DE) | 1986-03-12 | — | — | EP | disclosed |
| EP-0173317-A1 | Unsymmetrical sulfonyl guanidines | BAYER AG (DE) | 1986-03-05 | — | — | EP | disclosed |