Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.40 |
| ▸ | PRCP | P42785 | 1/20 | 0.40 |
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8596645 | 1.00 | LMNA (0.40) | LMNAUSP2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8693147 | 0.85 | PRCP (0.41) | LMNAUSP2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8693150 | 0.85 | PRCP (0.41) | LMNAUSP2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8490628 | 0.83 | PRCP (0.46) | PRCPIRAK4ADORA3ADORA2AADORA2B | |
| SCHEMBL8597662 | 0.83 | PRCP (0.41) | LMNAUSP2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8597660 | 0.83 | PRCP (0.41) | LMNAUSP2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8490623 | 0.83 | PRCP (0.46) | PRCPIRAK4ADORA3ADORA2AADORA2B | |
| SCHEMBL8705766 | 0.81 | HTR1A (0.38) | PRCPNSD2ALDH1A1HTR1AADRA1D | |
| SCHEMBL8595512 | 0.81 | PRCP (0.40) | CYP1A2CYP3A4CYP2D6PRCPIRAK4 | |
| SCHEMBL8595511 | 0.81 | PRCP (0.40) | CYP1A2CYP3A4CYP2D6PRCPIRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852023-A | Cyclohexylamino and cycloalkoxy nitrogen heterocycles, processes for their preparation, and their use as pesticides and fungicides | HOECHST SCHERING AGREVO GMBH (DE) | 1998-12-22 | — | — | US | disclosed |
| EP-0817774-A1 | CYCLOHEXYLAMINO AND CYCLOHEXYLALKOXY NITROGEN HETEROCYCLES, METHODS OF PREPARING THEM AND THEIR USE AS PEST-CONTROL AGENTS AND FUNGICIDES | Hoechst Schering AgrEvo GmbH (DE) | 1998-01-14 | — | — | EP | disclosed |
| WO-1996030345-A1 | CYCLOHEXYLAMINO AND CYCLOHEXYLALKOXY NITROGEN HETEROCYCLES, METHODS OF PREPARING THEM AND THEIR USE AS PEST-CONTROL AGENTS AND FUNGICIDES | HOECHST SCHERING AGREVO GMBH (DE) | 1996-10-03 | — | — | WO | disclosed |