SCHEMBL8596804

SCHEMBL8596804

CCCCCCCOC(C(=O)OC)C(F)(F)F

nearest known ligand 0.45

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CES2 O00748 2/20 0.45
ZDHHC7 Q9NXF8 1/20 0.45
EPHX1 P07099 2/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
NAAA Q02083 1/20 0.42
PLA2G2C Q5R387 1/20 0.40
FAAH O00519 1/20 0.39
ACHE P22303 6/20 0.39
TSHR P16473 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8597892 1.00 CES2 (0.45) CES2ZDHHC7EPHX1CA1CA2
SCHEMBL8599123 1.00 CES2 (0.45) CES2ZDHHC7EPHX1CA1CA2
SCHEMBL8595735 0.98 CA1 (0.44) CES2ZDHHC7EPHX1CA1CA2
SCHEMBL8600184 0.93 CA1 (0.46) CES2ZDHHC7EPHX1CA1CA2
SCHEMBL8599540 0.87 CES2 (0.45) CES2EPHX1NAAAPLA2G2CFAAH
SCHEMBL8598080 0.87 NAAA (0.46) CES2EPHX1NAAAFAAHACHE
SCHEMBL8595269 0.87 CES2 (0.45) CES2EPHX1NAAAFAAHTSHR
SCHEMBL8598819 0.87 NAAA (0.46) CES2EPHX1NAAAFAAHACHE
SCHEMBL8598140 0.87 CES2 (0.45) CES2EPHX1NAAAPLA2G2CFAAH
SCHEMBL8596289 0.87 CES2 (0.45) CES2EPHX1NAAAPLA2G2CFAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0592669-B1 OPTICALLY ACTIVE TRIFLUOROLACTIC ACID DERIVATIVE AND LIQUID CRYSTAL COMPOSITION CHISSO CORP (JP) 1998-01-28 EP disclosed
US-5665270-A Optically active trifluorolactic acid derivative and liquid crystal composition CHISSO CORPORATION (JP) 1997-09-09 US disclosed
EP-0592669-A1 OPTICALLY ACTIVE TRIFLUOROLACTIC ACID DERIVATIVE AND LIQUID CRYSTAL COMPOSITION CHISSO CORPORATION (JP) 1994-04-20 EP disclosed