Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 4/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 4/20 | 0.34 |
| ▸ | RAB9A | P51151 | 4/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | CASP3 | P42574 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9429714 | 0.81 | ABCG2 (0.36) | POLBSMN1; SMN2ABCG2NPC1RAB9A | |
| SCHEMBL27357705 | 0.80 | POLB (0.38) | POLBSMN1; SMN2ABCG2AOC3NPC1 | |
| SCHEMBL7015622 | 0.80 | PBRM1 (0.41) | POLBSMN1; SMN2ABCG2AOC3NPC1 | |
| SCHEMBL7020959 | 0.80 | POLB (0.36) | POLBSMN1; SMN2ABCG2AOC3NPC1 | |
| SCHEMBL9131392 | 0.79 | POLB (0.38) | POLBSMN1; SMN2ABCG2AOC3NPC1 | |
| SCHEMBL8788397 | 0.78 | NPSR1 (0.55) | SMN1; SMN2ABCG2NPC1RAB9AL3MBTL1 | |
| SCHEMBL9257119 | 0.78 | POLB (0.40) | POLBSMN1; SMN2ABCG2AOC3NPC1 | |
| SCHEMBL7020110 | 0.76 | POLB (0.36) | POLBSMN1; SMN2ABCG2AOC3NPC1 | |
| SCHEMBL9430611 | 0.76 | ABCG2 (0.45) | POLBSMN1; SMN2ABCG2AOC3NPC1 | |
| SCHEMBL6188044 | 0.76 | GRM5 (0.39) | POLBSMN1; SMN2ABCG2AOC3NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0593332-B1 | Phenylborinic acid derivatives, their preparation and their use as intermediates in syntheses | SYNTHELABO (FR) | 1998-01-14 | — | — | EP | disclosed |
| US-5382672-A | Preparation of derivatives of benzeneborinic acid | SYNTHELABO (FR) | 1995-01-17 | — | — | US | disclosed |
| US-5371233-A | 2-(tetrazol-5-yl)-1,1'-biphenyl derivatives, their preparation and their use as synthetic intermediates | SYNTHELABO (FR) | 1994-12-06 | — | — | US | disclosed |
| EP-0593332-A1 | Phenylboronic acid derivatives, their preparation and their use as intermediates in syntheses | SYNTHELABO (FR) | 1994-04-20 | — | — | EP | disclosed |
| US-5278312-A | Derivatives of benzeneborinic acid, preparation thereof and use thereof as synthetic intermediates | SYNTHELABO (FR) | 1994-01-11 | — | — | US | disclosed |
| EP-0550313-A1 | 2-(Tetranol-5-yl)-(1,1'-biphenyl)derivatives, their preparation and use as intermediates | SYNTHELABO (FR) | 1993-07-07 | — | — | EP | disclosed |