Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.41 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.40 |
| ▸ | GRM5 | P41594 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | XDH | P47989 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7346198 | 0.85 | NPSR1 (0.50) | NPSR1RECQLALDH1A1HPGDHSD17B10 | |
| SCHEMBL13846219 | 0.79 | NPSR1 (0.58) | NPSR1RECQLALDH1A1HSD17B10ABCB1 | |
| SCHEMBL8596999 | 0.78 | POLB (0.38) | NPSR1HPGDABCB1ABCG2KCNN4 | |
| SCHEMBL27357705 | 0.78 | POLB (0.38) | NPSR1HPGDABCG2NPC1RAB9A | |
| SCHEMBL9429885 | 0.76 | ABCG2 (0.40) | NPSR1RECQLHPGDABCB1ABCG2 | |
| SCHEMBL9257119 | 0.75 | POLB (0.40) | NPSR1RECQLHPGDABCB1ABCG2 | |
| SCHEMBL9430611 | 0.74 | ABCG2 (0.45) | NPSR1ALDH1A1HPGDABCG2NPC1 | |
| SCHEMBL7020110 | 0.74 | POLB (0.36) | NPSR1HPGDABCG2NPC1RAB9A | |
| SCHEMBL6188044 | 0.74 | GRM5 (0.39) | ALDH1A1HPGDABCG2KCNN4GRM5 | |
| SCHEMBL7020959 | 0.74 | POLB (0.36) | NPSR1HPGDABCG2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0760814-A1 | A PROCESS FOR PREPARING 1-BUTYL-2-[2'-(2H-TETRAZOL-5-YL)-BIPHENYL-4-YLMETHYL]-1H-INDOLE-3-CARBOXYLIC ACID | SYNTEX (U.S.A.) INC. (US) | 1997-03-12 | — | — | EP | disclosed |
| WO-1995032961-A1 | A PROCESS FOR PREPARING 1-BUTYL-2-[2'-(2H-TETRAZOL-5-YL)-BIPHENYL-4-YLMETHYL]-1H-INDOLE-3-CARBOXYLIC ACID | SYNTEX (U.S.A.) INC. (US) | 1995-12-07 | — | — | WO | disclosed |