Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 14/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CDK9 | P50750 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 6/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7118888 | 0.94 | KMT2A (0.38) | TLR8KMT2A | |
| SCHEMBL7117925 | 0.94 | KMT2A (0.38) | TLR8KMT2A | |
| SCHEMBL7126475 | 0.94 | KMT2A (0.38) | TLR8KMT2A | |
| SCHEMBL8602832 | 0.91 | MAPT (0.38) | KDM4EMAPTKMT2ASMN1; SMN2CA1 | |
| SCHEMBL8599188 | 0.84 | KMT2A (0.33) | KDM4ENPC1ALDH1A1LMNACASP3 | |
| SCHEMBL14269187 | 0.84 | CYP2D6 (0.40) | KDM4EALDH1A1MAPTHPGDKMT2A | |
| SCHEMBL14269189 | 0.82 | CYP2D6 (0.50) | KDM4EMEN1NPC1ALDH1A1MAPT | |
| SCHEMBL7640676 | 0.80 | TLR8 (0.40) | TLR8KDM4EL3MBTL1NPSR1MEN1 | |
| SCHEMBL7518385 | 0.80 | DNM2 (0.44) | TLR8L3MBTL1TLR7 | |
| SCHEMBL6398903 | 0.79 | TLR8 (0.38) | TLR8KDM4EL3MBTL1KMT2ATLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5772990-A | Composition for slowing down the loss of hair based on pyrimidine N-oxides triaminosubstituted or their sulfoconjugated | L'OREAL (FR) | 1998-06-30 | — | — | US | disclosed |