Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.35 |
| ▸ | DNM2 | P50570 | 3/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 6/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7118888 | 1.00 | KMT2A (0.38) | KMT2AABL1TLR8DNM2GPR84 | |
| SCHEMBL7117925 | 1.00 | KMT2A (0.38) | KMT2AABL1TLR8DNM2GPR84 | |
| SCHEMBL8597239 | 0.94 | TLR8 (0.40) | KMT2ATLR8 | |
| SCHEMBL8602832 | 0.88 | MAPT (0.38) | KMT2A | |
| SCHEMBL14269187 | 0.84 | CYP2D6 (0.40) | KMT2AGPR84 | |
| SCHEMBL8599188 | 0.82 | KMT2A (0.33) | KMT2A | |
| SCHEMBL7117980 | 0.81 | ACHE (0.36) | TLR8DNM2GPR84 | |
| SCHEMBL7118821 | 0.81 | ACHE (0.36) | TLR8DNM2GPR84 | |
| SCHEMBL7116982 | 0.81 | ACHE (0.36) | TLR8DNM2GPR84 | |
| SCHEMBL7115146 | 0.81 | ACHE (0.36) | TLR8DNM2GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6511659-B2 | Treatment of alopecia, cosmetics | SOCIETE L'OREAL S.A. (FR) | 2003-01-28 | — | — | US | claimed |
| US-6653317-B2 | Pyrimidine 3-oxide compounds for inducing/stimulating hair growth and/or retarding hair loss | SOCIETE L'OREAL S.A. (FR) | 2003-11-25 | — | — | US | disclosed |
| US-20030130294-A1 | Pyrimidine 3-oxide compounds for inducing/stimulating hair growth and/or retarding hair loss | MAHE YANN (FR) | 2003-07-10 | — | — | US | disclosed |
| US-6511659-B2 | Treatment of alopecia, cosmetics | SOCIETE L'OREAL S.A. (FR) | 2003-01-28 | — | — | US | disclosed |
| US-20010044444-A1 | Pyrimidine 3-oxide compounds for inducing/stimulating hair growth and/or retarding hair loss | MAHE YANN (FR) | 2001-11-22 | — | — | US | disclosed |
| US-6291468-B1 | Pyrimidine 3-oxide compounds for inducing/stimulating hair growth and/or retarding hair loss | SOCIETE L'OREAL S.A. (FR) | 2001-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030130294-A1 | Pyrimidine 3-oxide compounds for inducing/stimulating hair growth and/or retarding hair loss | TK2, TYR, MTR | KMT2A 1432/4885ABL1 1339/4885TLR8 3325/4885 |
| US-20010044444-A1 | Pyrimidine 3-oxide compounds for inducing/stimulating hair growth and/or retarding hair loss | TK2, TYR, MTR | KMT2A 1379/4885ABL1 1539/4885TLR8 3364/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.