Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP12 | P39900 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | KDM4A | O75164 | 1/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8598155 | 0.82 | TSHR (0.48) | TSHRKMT2ALMNAALDH1A1RAB9A | |
| SCHEMBL10515420 | 0.82 | TSHR (0.57) | TLR8TSHRKMT2ALMNAALDH1A1 | |
| SCHEMBL8554726 | 0.77 | ESR1 (0.44) | TSHRKMT2ALMNAALDH1A1RAB9A | |
| SCHEMBL7351293 | 0.77 | BCHE (0.44) | TLR8TSHRKMT2AALDH1A1RAB9A | |
| SCHEMBL11753672 | 0.71 | KDM4E (0.53) | TSHRKMT2ALMNAALDH1A1RAB9A | |
| SCHEMBL11749159 | 0.71 | KDM4E (0.53) | TSHRKMT2ALMNAALDH1A1RAB9A | |
| SCHEMBL11747508 | 0.71 | KDM4E (0.53) | TSHRKMT2ALMNAALDH1A1RAB9A | |
| SCHEMBL11747519 | 0.71 | KDM4E (0.53) | TSHRKMT2ALMNAALDH1A1RAB9A | |
| SCHEMBL11777317 | 0.71 | KDM4E (0.53) | TSHRKMT2ALMNAALDH1A1RAB9A | |
| SCHEMBL11751433 | 0.71 | KDM4E (0.53) | TSHRKMT2ALMNAALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0513966-B1 | Bis-bibenzimidazole composition | ZENECA LTD (GB) | 1998-04-29 | — | — | EP | disclosed |
| US-5258524-A | Solvent extraction of zinc | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-11-02 | — | — | US | disclosed |
| EP-0513966-A2 | Bis-bibenzimidazole composition | ZENECA LIMITED (GB) | 1992-11-19 | — | — | EP | disclosed |