Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.39 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8555403 | 0.86 | KMT2A (0.37) | ESR1KMT2ATSHRRAB9AMEN1 | |
| SCHEMBL10515420 | 0.82 | TSHR (0.57) | KMT2ATSHRRAB9AMEN1MAPT | |
| SCHEMBL8598151 | 0.77 | TLR8 (0.45) | ESR1KMT2ATSHRRAB9AMEN1 | |
| SCHEMBL8598155 | 0.75 | TSHR (0.48) | KMT2ATSHRRAB9AMEN1MAPT | |
| SCHEMBL5970046 | 0.69 | TSHR (0.58) | KMT2ATSHRRAB9AMEN1MAPT | |
| SCHEMBL3649939 | 0.69 | TSHR (0.41) | ESR1KMT2ATSHRRAB9AMEN1 | |
| SCHEMBL10513445 | 0.68 | TSHR (0.47) | KMT2ATSHRRAB9AMEN1MAPT | |
| SCHEMBL10513278 | 0.68 | TSHR (0.47) | KMT2ATSHRRAB9AMEN1MAPT | |
| SCHEMBL10516104 | 0.65 | TSHR (0.43) | ESR1TSHRRAB9AMAPTKDM4E | |
| SCHEMBL11881207 | 0.62 | NAAA (0.50) | ESR1TSHRRAB9AMAPTAKR1C4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0513966-B1 | Bis-bibenzimidazole composition | ZENECA LTD (GB) | 1998-04-29 | — | — | EP | claimed |
| US-5258524-A | Solvent extraction of zinc | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-11-02 | — | — | US | claimed |
| EP-0513966-A2 | Bis-bibenzimidazole composition | ZENECA LIMITED (GB) | 1992-11-19 | — | — | EP | claimed |
| EP-0513966-B1 | Bis-bibenzimidazole composition | ZENECA LTD (GB) | 1998-04-29 | — | — | EP | disclosed |
| US-5258524-A | Solvent extraction of zinc | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-11-02 | — | — | US | disclosed |
| EP-0513966-A2 | Bis-bibenzimidazole composition | ZENECA LIMITED (GB) | 1992-11-19 | — | — | EP | disclosed |