SCHEMBL8598271

SCHEMBL8598271

CCCCC[Mg]Cc1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 1/20 0.44
DNM1 Q05193 2/20 0.43
TP53 P04637 2/20 0.42
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
EPHX2 P34913 2/20 0.42
MAPK1 P28482 1/20 0.42
PKM P14618 1/20 0.42
HTT P42858 2/20 0.41
KCNH2 Q12809 1/20 0.41
CETP P11597 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL15019401 0.98 SIGMAR1 (0.43) SIGMAR1DNM1TP53MEN1KMT2A
SCHEMBL8602023 0.98 DNM1 (0.46) SIGMAR1DNM1TP53MEN1KMT2A
Hydrochloric Acid SCHEMBL28181422 0.96 DNM1 (0.44) SIGMAR1DNM1TP53MEN1KMT2A
Hydrochloric Acid SCHEMBL27986874 0.96 SIGMAR1 (0.42) SIGMAR1DNM1TP53MEN1KMT2A
Hydrochloric Acid SCHEMBL28190960 0.94 DNM1 (0.43) SIGMAR1DNM1TP53MEN1KMT2A
Hydrochloric Acid SCHEMBL28116837 0.94 DNM1 (0.43) SIGMAR1DNM1TP53MEN1KMT2A
Hydrochloric Acid SCHEMBL27987305 0.94 DNM1 (0.43) SIGMAR1DNM1TP53MEN1KMT2A
SCHEMBL8601778 0.94 TP53 (0.42) SIGMAR1DNM1TP53MEN1KMT2A
Hydrochloric Acid SCHEMBL23794958 0.92 TP53 (0.41) SIGMAR1DNM1TP53MEN1KMT2A
Iodide SCHEMBL11691633 0.92 TP53 (0.41) SIGMAR1DNM1TP53MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0571945-B1 Catalyst for copolymerizing ethylene with alpha-olefin and process for producing ethylene-alpha-olefin copolymer using the catalyst SUMITOMO CHEMICAL CO (JP) 1998-02-04 EP disclosed
US-5602223-A RADIATION TRANSPARENT, GLOSS, MELT TENSION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-02-11 US disclosed
EP-0571945-A2 Catalyst for copolymerizing ethylene with alpha-olefin and process for producing ethylene-alpha-olefin copolymer using the catalyst SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-12-01 EP disclosed