Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.46 |
| ▸ | ACHE | P22303 | 2/20 | 0.44 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7048071 | 0.72 | HSP90AA1 (0.50) | KMT2AL3MBTL1ALDH1A1POLBMAPK1 | |
| SCHEMBL16674109 | 0.72 | HSP90AA1 (0.59) | KMT2AL3MBTL1ALDH1A1POLBMAPK1 | |
| SCHEMBL297246 | 0.72 | HSP90AA1 (0.50) | KMT2AL3MBTL1ALDH1A1POLBMAPK1 | |
| SCHEMBL8120184 | 0.72 | KMT2A (0.50) | KMT2AL3MBTL1ALDH1A1POLBMAPK1 | |
| Hydrochloric Acid SCHEMBL713375 | 0.71 | HSP90AA1 (0.53) | KMT2AL3MBTL1ALDH1A1POLBMAPK1 | |
| Hydrochloric Acid SCHEMBL5847774 | 0.71 | HSP90AA1 (0.53) | KMT2AL3MBTL1ALDH1A1POLBMAPK1 | |
| SCHEMBL7045863 | 0.69 | HSP90AA1 (0.47) | KMT2AL3MBTL1ALDH1A1POLBMAPK1 | |
| SCHEMBL5327423 | 0.69 | LMNA (0.53) | KMT2AL3MBTL1ALDH1A1POLBMAPK1 | |
| SCHEMBL8432632 | 0.68 | HSP90AA1 (0.54) | KMT2AL3MBTL1ALDH1A1POLBMAPK1 | |
| SCHEMBL13965280 | 0.68 | KMT2A (0.55) | KMT2AL3MBTL1ALDH1A1POLBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5726314-A | ACETYLCHOLINESTERASE INHIBITORS AS NERVE AGENT ANTIDOTES | GEORGIA TECH RESEARCH CORP. (US) | 1998-03-10 | — | — | US | disclosed |