SCHEMBL8599100

SCHEMBL8599100

CC[C@H](C)[C@H](N)C(=O)NC[C@H]1CC[C@H](C(=O)O)CC1

nearest known ligand 0.52

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.52
PLG P00747 1/20 0.42
PLAT P00750 1/20 0.42
LMNA P02545 1/20 0.42
ANPEP P15144 1/20 0.42
ENPEP Q07075 1/20 0.42
POLB P06746 1/20 0.41
TDP1 Q9NUW8 1/20 0.40
MEN1 O00255 1/20 0.39
DPP4 P27487 2/20 0.38
FAP Q12884 2/20 0.38
DPP8 Q6V1X1 2/20 0.38
DPP9 Q86TI2 2/20 0.38
DPP7 Q9UHL4 2/20 0.38
ARG1 P05089 2/20 0.38
ARG2 P78540 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL8596530 0.99 KMT2A (0.51) KMT2APLGPLATLMNAANPEP
SCHEMBL8597460 0.88 KMT2A (0.54) KMT2APLGPLATLMNAANPEP
SCHEMBL8598968 0.87 KMT2A (0.53) KMT2APLGPLATLMNAANPEP
SCHEMBL8596277 0.84 KMT2A (0.57) KMT2APLGPLATLMNAANPEP
SCHEMBL8595943 0.81 KMT2A (0.59) KMT2APLGPLATLMNAANPEP
SCHEMBL8595946 0.81 KMT2A (0.59) KMT2APLGPLATLMNAANPEP
SCHEMBL2140856 0.81 DPP4 (0.44) TDP1DPP4FAPDPP8DPP9
SCHEMBL3633232 0.81 ALOX15 (0.47) ANPEPDPP4FAPDPP8DPP9
SCHEMBL2142965 0.81 DPP4 (0.42) TDP1DPP4FAPDPP8DPP9
SCHEMBL9034247 0.80 DPP4 (0.38) KMT2ATDP1DPP4FAPDPP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0585130-B1 External preparation for skin containing a depigmentation agent SHISEIDO CO LTD (JP) 1998-01-28 EP disclosed
US-5690914-A TRANEXAMIC ACID DERIVATIVES FOR DEPIGMENTATION SHISEIDO CO., LTD (JP) 1997-11-25 US disclosed