Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 10/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 6/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 5/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 4/20 | 0.36 |
| ▸ | FAP | Q12884 | 2/20 | 0.36 |
| ▸ | TERT | O14746 | 1/20 | 0.35 |
| ▸ | ARG1 | P05089 | 2/20 | 0.34 |
| ▸ | ARG2 | P78540 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8599100 | 0.80 | KMT2A (0.52) | DPP4TDP1DPP8DPP9DPP7 | |
| Hydrochloric Acid SCHEMBL8596530 | 0.79 | KMT2A (0.51) | DPP4TDP1DPP8DPP9DPP7 | |
| SCHEMBL2142965 | 0.78 | DPP4 (0.42) | DPP4TDP1DPP8DPP9DPP7 | |
| SCHEMBL2140856 | 0.78 | DPP4 (0.44) | DPP4TDP1DPP8DPP9DPP7 | |
| SCHEMBL3633232 | 0.78 | ALOX15 (0.47) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL2142676 | 0.77 | DPP4 (0.44) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL9033807 | 0.77 | DPP4 (0.35) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL3634209 | 0.76 | DPP4 (0.49) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL16559588 | 0.75 | ARG1 (0.50) | DPP4TDP1DPP8DPP9DPP7 | |
| SCHEMBL12310946 | 0.75 | ARG1 (0.50) | DPP4TDP1DPP8DPP9DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696593-A2 | Inhibitors of farnesyl protein transferase | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-02-14 | — | — | EP | disclosed |