Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 6/20 | 0.71 |
| ▸ | DRD2 | P14416 | 5/20 | 0.71 |
| ▸ | DRD4 | P21917 | 5/20 | 0.71 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.71 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.71 |
| ▸ | HRH2 | P25021 | 3/20 | 0.71 |
| ▸ | HTR2A | P28223 | 3/20 | 0.71 |
| ▸ | HTR7 | P34969 | 3/20 | 0.71 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.71 |
| ▸ | HRH1 | P35367 | 3/20 | 0.71 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.71 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.71 |
| ▸ | DRD3 | P35462 | 3/20 | 0.71 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.71 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.71 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.71 |
| ▸ | DRD1 | P21728 | 2/20 | 0.71 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.71 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.71 |
| ▸ | HTR2C | P28335 | 2/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8595342 | 0.98 | HTR1A (0.74) | HTR1ADRD2DRD4ADRA2AADRA2C | |
| SCHEMBL8595084 | 0.88 | HTR1A (0.71) | HTR1ADRD2DRD4ADRA2AADRA2C | |
| SCHEMBL8597811 | 0.88 | HTR1A (0.63) | HTR1ADRD2DRD4ADRA2AADRA2C | |
| SCHEMBL8598448 | 0.87 | HTR1A (0.57) | HTR1ADRD2DRD4ADRA2AADRA2C | |
| SCHEMBL8595370 | 0.86 | HTR1A (0.66) | HTR1ADRD2DRD4ADRA2AADRA2C | |
| SCHEMBL8595848 | 0.85 | HTR1A (0.60) | HTR1ADRD2DRD4ADRA2AADRA2C | |
| SCHEMBL4546509 | 0.83 | HTR1A (1.00) | HTR1ADRD2DRD4ADRA2AADRA2C | |
| SCHEMBL8598471 | 0.82 | HTR1A (0.57) | HTR1ADRD2DRD4ADRA2AADRA2C | |
| SCHEMBL8597149 | 0.81 | HTR1A (0.53) | HTR1ADRD2DRD4ADRA2AADRA2C | |
| SCHEMBL8597120 | 0.81 | HTR1A (0.51) | HTR1ADRD2HTR2AHTR7DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0875512-A2 | New naphthylpiperazine derivatives with antipsychotic activity | FABRICA ESPANOLA DE PRODUCTOS QUIMICOS Y FARMACEUTICOS, S.A. (FAES) (ES) | 1998-11-04 | — | — | EP | claimed |