Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 18/20 | 0.49 |
| ▸ | FLT3 | P36888 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8602447 | 0.92 | IRAK4 (0.52) | IRAK4FLT3 | |
| SCHEMBL8596516 | 0.92 | IRAK4 (0.49) | IRAK4FLT3 | |
| SCHEMBL13990316 | 0.91 | IRAK4 (0.49) | IRAK4FLT3MAPT | |
| SCHEMBL8601241 | 0.89 | IRAK4 (0.46) | IRAK4FLT3MAPT | |
| SCHEMBL8602825 | 0.86 | TSHR (0.52) | IRAK4FLT3MAPT | |
| SCHEMBL8565463 | 0.85 | IRAK4 (0.48) | IRAK4FLT3 | |
| SCHEMBL8602584 | 0.84 | IRAK4 (0.44) | IRAK4FLT3MAPT | |
| SCHEMBL8602071 | 0.83 | MAPT (0.46) | IRAK4FLT3MAPT | |
| SCHEMBL8670347 | 0.81 | MAPT (0.48) | IRAK4MAPT | |
| SCHEMBL8597477 | 0.79 | ALDH1A1 (0.46) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863881-A1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE IN THE PREVENTION AND/OR THE TREATMENT OF BONE DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-09-16 | — | — | EP | disclosed |
| WO-1997010219-A1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE IN THE PREVENTION AND/OR THE TREATMENT OF BONE DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-03-20 | — | — | WO | disclosed |