SCHEMBL8599178

SCHEMBL8599178

CCOC(=O)c1ccc(-n2c(C)cc(C=O)c2C)cc1

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 12/20 0.75
LMNA P02545 3/20 0.75
SMN1; SMN2 Q16637 1/20 0.75
HTT P42858 2/20 0.62
HPGD P15428 2/20 0.62
MAPT P10636 4/20 0.58
POLB P06746 4/20 0.55
L3MBTL1 Q9Y468 4/20 0.55
KDM4E B2RXH2 4/20 0.55
CTDSP1 Q9GZU7 3/20 0.55
CASP6 P55212 2/20 0.55
APEX1 P27695 3/20 0.53
TDP1 Q9NUW8 3/20 0.53
MAPK1 P28482 1/20 0.53
MEN1 O00255 4/20 0.51
KMT2A Q03164 4/20 0.51
NSD2 O96028 1/20 0.51
PKM P14618 1/20 0.51
CASP3 P42574 1/20 0.51
RECQL P46063 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9319310 0.87 ALDH1A1 (0.58) ALDH1A1LMNASMN1; SMN2HTTHPGD
SCHEMBL24251266 0.82 HPGD (0.53) ALDH1A1LMNASMN1; SMN2HTTHPGD
SCHEMBL7825875 0.81 POLB (0.75) ALDH1A1LMNASMN1; SMN2HTTHPGD
SCHEMBL15331075 0.80 POLB (0.60) ALDH1A1LMNASMN1; SMN2HTTHPGD
SCHEMBL24251253 0.78 ALDH1A1 (0.56) ALDH1A1LMNASMN1; SMN2HTTHPGD
SCHEMBL10405471 0.78 POLB (0.57) ALDH1A1LMNASMN1; SMN2HTTHPGD
SCHEMBL8597363 0.78 HTT (1.00) ALDH1A1LMNASMN1; SMN2HTTHPGD
SCHEMBL24251267 0.78 ALDH1A1 (0.48) ALDH1A1LMNASMN1; SMN2HTTHPGD
SCHEMBL13846859 0.78 NPC1 (0.69) LMNAHPGDMAPTPOLBKDM4E
SCHEMBL24943173 0.77 ALDH1A1 (0.47) ALDH1A1LMNASMN1; SMN2HTTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220049068-A1 RESIN COMPOSITION, LIQUID COMPOSITION, COLORING AGENT COMPOUND, AND OPTICAL MATERIAL FUJIFILM CORPORATION (JP) 2022-02-17 US disclosed
EP-0519306-B1 Oil-dispersed yellow filter dyes FUJI PHOTO FILM CO LTD (JP) 1998-02-04 EP disclosed
US-5328818-A Support with color couplers in emulsions in multilayer element FUJI PHOTO FILM CO., LTD. (JP) 1994-07-12 US disclosed
US-5296344-A Silver halide photographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 1994-03-22 US disclosed
EP-0519306-A1 Oil-dispersed yellow filter dyes FUJI PHOTO FILM CO., LTD. (JP) 1992-12-23 EP disclosed