Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 8/20 | 0.75 |
| ▸ | L3MBTL1 | Q9Y468 | 7/20 | 0.75 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.75 |
| ▸ | CTDSP1 | Q9GZU7 | 3/20 | 0.75 |
| ▸ | CASP6 | P55212 | 2/20 | 0.75 |
| ▸ | HTT | P42858 | 1/20 | 0.75 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.72 |
| ▸ | APEX1 | P27695 | 4/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 16/20 | 0.68 |
| ▸ | RECQL | P46063 | 2/20 | 0.64 |
| ▸ | NSD2 | O96028 | 1/20 | 0.64 |
| ▸ | PKM | P14618 | 1/20 | 0.64 |
| ▸ | CASP3 | P42574 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 5/20 | 0.62 |
| ▸ | MEN1 | O00255 | 4/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15331075 | 0.86 | POLB (0.60) | POLBL3MBTL1KDM4ECTDSP1CASP6 | |
| SCHEMBL15331958 | 0.84 | POLB (1.00) | POLBL3MBTL1KDM4ECTDSP1CASP6 | |
| SCHEMBL10405471 | 0.84 | POLB (0.57) | POLBL3MBTL1KDM4ECTDSP1CASP6 | |
| SCHEMBL17802297 | 0.82 | ALDH1A1 (0.65) | POLBL3MBTL1KDM4ECTDSP1CASP6 | |
| SCHEMBL645648 | 0.82 | POLB (0.68) | POLBL3MBTL1KDM4ECTDSP1CASP6 | |
| SCHEMBL8599178 | 0.81 | ALDH1A1 (0.75) | POLBL3MBTL1KDM4ECTDSP1CASP6 | |
| SCHEMBL2560918 | 0.81 | KLKB1 (0.60) | POLBL3MBTL1KDM4ECTDSP1CASP6 | |
| SCHEMBL15331428 | 0.81 | ALDH1A1 (1.00) | POLBL3MBTL1KDM4ECTDSP1CASP6 | |
| SCHEMBL2562958 | 0.81 | ALDH1A1 (0.80) | POLBL3MBTL1KDM4ECTDSP1CASP6 | |
| SCHEMBL21225472 | 0.79 | ALDH1A1 (0.62) | POLBL3MBTL1KDM4ECTDSP1CASP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| US-11225655-B2 | Bi-functional complexes and methods for making and using such complexes | NUEVOLUTION A/S (DK) | 2022-01-18 | — | — | US | disclosed |
| EP-3540059-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2019-09-18 | — | — | EP | disclosed |
| EP-2558577-B1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION AS (DK) | 2018-12-12 | — | — | EP | disclosed |
| US-20130281324-A1 | BI-FUNCTINAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2013-10-24 | — | — | US | disclosed |
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |