Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | MGAM | O43451 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SI | P14410 | 1/20 | 0.46 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL283994 | 0.93 | GAA (0.52) | TSHRCYP1A2MGAMGAASI | |
| SCHEMBL8603687 | 0.92 | TSHR (0.46) | TSHRCYP1A2MGAMGAASI | |
| SCHEMBL5016265 | 0.89 | LMNA (0.58) | TSHRCYP1A2MGAMGAASI | |
| SCHEMBL11441718 | 0.87 | CYP1A2 (0.47) | TSHRCYP1A2MGAMGAASI | |
| SCHEMBL29135741 | 0.83 | TSHR (0.52) | TSHRTDP1KMT2ALMNAHSD17B10 | |
| SCHEMBL11430132 | 0.83 | CYP1A2 (0.47) | TSHRCYP1A2MGAMGAASI | |
| SCHEMBL363334 | 0.81 | MGAM (0.55) | TSHRCYP1A2MGAMGAASI | |
| Succinic Acid Diethyl Ester SCHEMBL27966388 | 0.81 | MGAM (0.55) | TSHRCYP1A2MGAMGAASI | |
| Succinic Acid Diethyl Ester SCHEMBL27830938 | 0.81 | MGAM (0.55) | TSHRCYP1A2MGAMGAASI | |
| SCHEMBL262913 | 0.81 | MGAM (0.55) | TSHRCYP1A2MGAMGAASI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180240674-A1 | PASSIVATION OF GERMANIUM SURFACES | TRUIST BANK, AS NOTES COLLATERAL AGENT | 2018-08-23 | — | — | US | claimed |
| US-10934439-B2 | Additives for coating compositions and related methods | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2021-03-02 | — | — | US | disclosed |
| CN-105408446-B | The manufacture method of photochromic optical material | 三井化学株式会社 | 2018-01-09 | — | — | CN | disclosed |
| US-5821382-A | REACTING UNSATURATED COMPOUND AND HYDROGEN SULFIDE IN PRESENCE OF NITROGEN-CONTAINING COMPOUND SELECTED FROM SUBSTITUTED OR UNSUBSTITUTED AMIDES OR UREAS AND POLYSULFIDE COMPOUND OR SULFUR | NIPPON SHOKUBAI CO., LTD. (JP) | 1998-10-13 | — | — | US | disclosed |
| EP-0825179-A1 | PROCESS FOR THE PREPARATION OF THIOL COMPOUNDS | Nippon Shokubai Kagaku Kogyo Co., Ltd (JP) | 1998-02-25 | — | — | EP | disclosed |