Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | DGKA | P23743 | 1/20 | 0.44 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | PLA2G4B | P0C869 | 4/20 | 0.41 |
| ▸ | PAM | P19021 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | TOP2A | P11388 | 1/20 | 0.37 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.37 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL283830 | 0.94 | DGKA (0.48) | TSHRDGKALMNAL3MBTL1HCAR2 | |
| SCHEMBL5014579 | 0.90 | LMNA (0.54) | TSHRDGKAFFAR3HDAC3HDAC1 | |
| SCHEMBL31205753 | 0.85 | NAAA (0.56) | TSHRDGKAPLA2G4BPAMKMT2A | |
| SCHEMBL27450930 | 0.85 | NAAA (0.56) | TSHRDGKAPLA2G4BPAMKMT2A | |
| SCHEMBL30696100 | 0.85 | NAAA (0.56) | TSHRDGKAPLA2G4BPAMKMT2A | |
| SCHEMBL8599182 | 0.83 | TSHR (0.56) | TSHRFFAR3HDAC3HDAC1HDAC2 | |
| SCHEMBL20590 | 0.83 | DGKA (0.50) | TSHRDGKAFFAR3HDAC3HDAC1 | |
| SCHEMBL12456987 | 0.82 | DGKA (0.55) | TSHRDGKAPLA2G4BPAMHCAR2 | |
| SCHEMBL109395 | 0.81 | DGKA (0.48) | TSHRDGKAPLA2G4BLMNAKMT2A | |
| Hydrochloric Acid SCHEMBL11874724 | 0.81 | DGKA (0.48) | TSHRDGKAFFAR3HDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117229160-B | Triester cationic lipid compounds, compositions containing same and uses thereof | 北京悦康科创医药科技股份有限公司 | 2024-03-08 | — | — | CN | disclosed |
| CN-117229160-A | Triester cationic lipid compounds, compositions containing same and uses thereof | 北京悦康科创医药科技股份有限公司 | 2023-12-15 | — | — | CN | disclosed |