Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.42 |
| ▸ | PRNP | P04156 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | GLA | P06280 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8603065 | 0.86 | KDM4E (0.48) | ALDH1A1MAPTHSD17B10HPGDTP53 | |
| SCHEMBL8599957 | 0.85 | CCNB2 (0.35) | ALDH1A1MAPTKMT2APOLBRXFP1 | |
| SCHEMBL8598571 | 0.85 | ALDH1A1 (0.42) | ALDH1A1MAPTHSD17B10HPGDKMT2A | |
| SCHEMBL8603159 | 0.84 | ALDH1A1 (0.42) | ALDH1A1HSD17B10HPGDTP53POLB | |
| SCHEMBL8601923 | 0.82 | FABP4 (0.40) | ALDH1A1RXFP1PRNPKDM4ECYP1A2 | |
| SCHEMBL8599557 | 0.82 | ALDH1A1 (0.43) | ALDH1A1MAPTHSD17B10HPGDKMT2A | |
| SCHEMBL8603934 | 0.82 | MAPT (0.33) | ALDH1A1MAPTHSD17B10HPGDKMT2A | |
| SCHEMBL8602507 | 0.81 | TDP1 (0.34) | ALDH1A1MAPTHSD17B10HPGDKMT2A | |
| SCHEMBL8603132 | 0.81 | ALDH1A1 (0.41) | ALDH1A1MAPTHSD17B10KMT2APOLB | |
| SCHEMBL8598803 | 0.79 | ALDH1A1 (0.39) | ALDH1A1MAPTHSD17B10HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0626370-B1 | Process for producing aromatic isothiocyanate derivatives | SUMITOMO CHEMICAL CO (JP) | 1998-02-11 | — | — | EP | disclosed |
| US-5631209-A | ALGICIDES | ROHM AND HAAS COMPANY (US) | 1997-05-20 | — | — | US | disclosed |
| EP-0523244-B1 | SALT OF DITHIOCARBAMIC ACID, PRODUCTION THEREOF, AND PRODUCTION OF ISOTHIOCYANATE FROM SAID SALT | IHARA CHEMICAL IND CO (JP) | 1996-04-10 | — | — | EP | disclosed |
| EP-0415642-B1 | Glutarimides | ROHM & HAAS (US) | 1995-12-06 | — | — | EP | disclosed |
| US-5393735-A | N-(halo-oxy-)phenyl substituted cyclic imides | ROHM AND HAAS COMPANY (US) | 1995-02-28 | — | — | US | disclosed |
| EP-0626370-A1 | Process for producing aromatic isothiocyanate derivatives | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1994-11-30 | — | — | EP | disclosed |
| EP-0415641-B1 | Substituted glutaramic acids and derivatives | ROHM & HAAS (US) | 1994-01-19 | — | — | EP | disclosed |
| US-5274166-A | Dithiocarbamic acid salt, process for production thereof, and process for production of isothiocyanate using said dithiocarbamic acid salt | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 1993-12-28 | — | — | US | disclosed |
| US-5238908-A | HERBICIDAL GLUTARAMIC ACIDS AND DERIVATIVES | ROHM AND HAAS COMPANY (US) | 1993-08-24 | — | — | US | disclosed |
| EP-0523244-A1 | SALT OF DITHIOCARBAMIC ACID, PRODUCTION THEREOF, AND PRODUCTION OF ISOTHIOCYANATE FROM SAID SALT | IHARA CHEMICAL INDUSTRY Co., Ltd. (JP) | 1993-01-20 | — | — | EP | disclosed |
| EP-0415641-A1 | Substituted glutaramic acids and derivatives | ROHM AND HAAS COMPANY (US) | 1991-03-06 | — | — | EP | disclosed |
| EP-0415642-A1 | Glutarimides | ROHM AND HAAS COMPANY (US) | 1991-03-06 | — | — | EP | disclosed |