Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.30 |
| ▸ | MAPT | P10636 | 3/20 | 0.30 |
| ▸ | HTT | P42858 | 3/20 | 0.30 |
| ▸ | POLB | P06746 | 2/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 2/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8599258 | 1.00 | KMT2A (0.33) | KMT2AMEN1ALDH1A1MAPTHTT | |
| SCHEMBL8568096 | 0.82 | KMT2A (0.38) | KMT2AMEN1ALDH1A1MAPTHTT | |
| SCHEMBL8568101 | 0.82 | KMT2A (0.38) | KMT2AMEN1ALDH1A1MAPTHTT | |
| SCHEMBL8567625 | 0.80 | KMT2A (0.41) | KMT2AMEN1ALDH1A1MAPTHTT | |
| SCHEMBL8567627 | 0.80 | KMT2A (0.41) | KMT2AMEN1ALDH1A1MAPTHTT | |
| SCHEMBL8565614 | 0.78 | MAPT (0.33) | KMT2AMEN1ALDH1A1MAPTRAB9A | |
| SCHEMBL8565616 | 0.78 | MAPT (0.33) | KMT2AMEN1ALDH1A1MAPTRAB9A | |
| SCHEMBL8561307 | 0.75 | MEN1 (0.35) | KMT2AMEN1ALDH1A1MAPTHTT | |
| SCHEMBL8561311 | 0.75 | MEN1 (0.35) | KMT2AMEN1ALDH1A1MAPTHTT | |
| SCHEMBL8563923 | 0.75 | ALDH1A1 (0.33) | ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |