Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.30 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.30 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 2/20 | 0.30 |
| ▸ | RAB9A | P51151 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.30 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8565616 | 1.00 | MAPT (0.33) | MAPTLMNAALDH1A1HPGDALOX15 | |
| SCHEMBL8564865 | 0.80 | ALK (0.46) | MAPTALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL8599258 | 0.78 | KMT2A (0.33) | MAPTLMNAALDH1A1MEN1KMT2A | |
| SCHEMBL8599262 | 0.78 | KMT2A (0.33) | MAPTLMNAALDH1A1MEN1KMT2A | |
| SCHEMBL8566303 | 0.77 | MAPT (0.40) | MAPTLMNAMEN1USP2KMT2A | |
| SCHEMBL8566306 | 0.77 | MAPT (0.40) | MAPTLMNAMEN1USP2KMT2A | |
| SCHEMBL8568414 | 0.77 | RAB9A (0.40) | MAPTALDH1A1MEN1KMT2ANFE2L2 | |
| SCHEMBL8568417 | 0.77 | RAB9A (0.40) | MAPTALDH1A1MEN1KMT2ANFE2L2 | |
| SCHEMBL8141010 | 0.73 | HTT (0.37) | MAPTLMNAALDH1A1HPGDALOX15 | |
| SCHEMBL8559630 | 0.72 | IDO1 (0.33) | MAPTLMNAALDH1A1HPGDALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |