Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | SAE1 | Q9UBE0 | 2/20 | 0.41 |
| ▸ | UBA2 | Q9UBT2 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 6/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | TYK2 | P29597 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8597312 | 0.85 | TP53 (0.43) | MEN1KMT2ASMN1; SMN2TYK2HTT | |
| SCHEMBL8595623 | 0.85 | TYK2 (0.41) | MEN1KMT2ASMN1; SMN2TYK2HTT | |
| SCHEMBL8599983 | 0.84 | TYK2 (0.40) | MEN1KMT2ASMN1; SMN2NPC1TYK2 | |
| SCHEMBL8596165 | 0.84 | TP53 (0.45) | MEN1KMT2ASMN1; SMN2TYK2HTT | |
| SCHEMBL8598065 | 0.84 | TYK2 (0.40) | MEN1KMT2ASMN1; SMN2NPC1TYK2 | |
| SCHEMBL8596379 | 0.84 | TYK2 (0.41) | MEN1KMT2AALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL8597372 | 0.84 | PTGES (0.45) | MEN1KMT2ATYK2PTGESTP53 | |
| SCHEMBL8598251 | 0.84 | TYK2 (0.39) | MEN1KMT2ASMN1; SMN2TYK2HTT | |
| SCHEMBL8596861 | 0.84 | TP53 (0.40) | MEN1KMT2ASMN1; SMN2NPC1TYK2 | |
| Hydrochloric Acid SCHEMBL8602822 | 0.83 | MEN1 (0.45) | MEN1KMT2AKDM4EMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863881-A1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE IN THE PREVENTION AND/OR THE TREATMENT OF BONE DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-09-16 | — | — | EP | disclosed |
| WO-1997010219-A1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE IN THE PREVENTION AND/OR THE TREATMENT OF BONE DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-03-20 | — | — | WO | disclosed |