Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | PLK1 | P53350 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8600865 | 0.82 | CHRM1 (0.36) | HTTTSHRCHRM1POLBPLK1 | |
| SCHEMBL8602191 | 0.81 | CHRM1 (0.37) | HTTTSHRCHRM1POLBPLK1 | |
| SCHEMBL8603544 | 0.81 | CHRM1 (0.48) | CHRM1POLBCYP1A2CYP2C19 | |
| SCHEMBL8598841 | 0.81 | CHRM1 (0.36) | HTTTSHRCHRM1POLBPLK1 | |
| SCHEMBL8653570 | 0.80 | CHRM1 (0.43) | HTTCHRM1 | |
| SCHEMBL8598727 | 0.80 | CHRM1 (0.37) | HTTTSHRCHRM1POLBPLK1 | |
| SCHEMBL8600602 | 0.80 | CHRM1 (0.47) | CHRM1POLB | |
| SCHEMBL8598735 | 0.80 | CHRM1 (0.37) | HTTTSHRCHRM1POLBPLK1 | |
| SCHEMBL8602494 | 0.80 | CHRM1 (0.37) | HTTTSHRCHRM1POLBPLK1 | |
| SCHEMBL8603598 | 0.80 | CHRM1 (0.38) | HTTTSHRCHRM1POLBPLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0626370-B1 | Process for producing aromatic isothiocyanate derivatives | SUMITOMO CHEMICAL CO (JP) | 1998-02-11 | — | — | EP | disclosed |
| EP-0626370-A1 | Process for producing aromatic isothiocyanate derivatives | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1994-11-30 | — | — | EP | disclosed |