Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 2/20 | 0.36 |
| ▸ | PLK1 | P53350 | 1/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | PIK3C2A | O00443 | 2/20 | 0.31 |
| ▸ | PIK3C2B | O00750 | 2/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.31 |
| ▸ | PRKDC | P78527 | 2/20 | 0.31 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.31 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | KMO | O15229 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9694964 | 0.90 | CHRM1 (0.36) | CHRM1PLK1PIK3CGPOLBTSHR | |
| SCHEMBL8598735 | 0.87 | CHRM1 (0.37) | CHRM1PLK1PIK3CGPOLBTSHR | |
| SCHEMBL8598727 | 0.87 | CHRM1 (0.37) | CHRM1PLK1PIK3CGPOLBTSHR | |
| SCHEMBL8602494 | 0.87 | CHRM1 (0.37) | CHRM1PLK1PIK3CGPOLBTSHR | |
| SCHEMBL8598841 | 0.83 | CHRM1 (0.36) | CHRM1PLK1PIK3CGPOLBTSHR | |
| SCHEMBL8599276 | 0.82 | HTT (0.39) | CHRM1PLK1POLBTSHRHTT | |
| SCHEMBL8602191 | 0.81 | CHRM1 (0.37) | CHRM1PLK1POLBTSHRHTT | |
| SCHEMBL8603544 | 0.81 | CHRM1 (0.48) | CHRM1POLBCHRM5CHRM3 | |
| SCHEMBL8653570 | 0.80 | CHRM1 (0.43) | CHRM1PIK3CGHTTCHRM5CHRM3 | |
| SCHEMBL8600602 | 0.80 | CHRM1 (0.47) | CHRM1POLBCHRM5CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0626370-B1 | Process for producing aromatic isothiocyanate derivatives | SUMITOMO CHEMICAL CO (JP) | 1998-02-11 | — | — | EP | disclosed |
| EP-0626370-A1 | Process for producing aromatic isothiocyanate derivatives | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1994-11-30 | — | — | EP | disclosed |