Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 2/20 | 0.47 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.46 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 5/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PDE5A | O76074 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8603544 | 0.97 | CHRM1 (0.48) | CHRM1CHRM5CHRM3SCN9AEGFR | |
| SCHEMBL8653570 | 0.89 | CHRM1 (0.43) | CHRM1CHRM5CHRM3EGFR | |
| SCHEMBL10621790 | 0.82 | CHRM1 (0.45) | CHRM1CHRM5CHRM3EGFRPOLB | |
| SCHEMBL8603598 | 0.82 | CHRM1 (0.38) | CHRM1CHRM5CHRM3POLB | |
| SCHEMBL8602191 | 0.81 | CHRM1 (0.37) | CHRM1CHRM5CHRM3POLB | |
| SCHEMBL8599958 | 0.81 | CYP11B2 (0.38) | CHRM1 | |
| SCHEMBL8598841 | 0.81 | CHRM1 (0.36) | CHRM1CHRM5CHRM3POLB | |
| SCHEMBL8598735 | 0.80 | CHRM1 (0.37) | CHRM1CHRM5CHRM3POLB | |
| SCHEMBL8602494 | 0.80 | CHRM1 (0.37) | CHRM1CHRM5CHRM3POLB | |
| SCHEMBL8599276 | 0.80 | HTT (0.39) | CHRM1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0626370-B1 | Process for producing aromatic isothiocyanate derivatives | SUMITOMO CHEMICAL CO (JP) | 1998-02-11 | — | — | EP | disclosed |
| EP-0626370-A1 | Process for producing aromatic isothiocyanate derivatives | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1994-11-30 | — | — | EP | disclosed |