Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTAFR | P25105 | 5/20 | 0.46 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 5/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 5/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8600416 | 0.88 | PTAFR (0.36) | PTAFR | |
| SCHEMBL8603103 | 0.88 | PTAFR (0.43) | PTAFRACE2AKR1C3AKR1C2CYP2C9 | |
| SCHEMBL8604338 | 0.83 | CYP11B1 (0.42) | PTAFRCYP11B1CYP11B2CYP19A1 | |
| SCHEMBL8602425 | 0.80 | PTAFR (0.35) | PTAFRACE2AKR1C3AKR1C2CNR1 | |
| SCHEMBL8600391 | 0.80 | PTAFR (0.40) | PTAFRCYP11B1CYP11B2PPARACYP19A1 | |
| SCHEMBL8603644 | 0.80 | PTAFR (0.39) | PTAFRACE2AKR1C3AKR1C2CYP2C9 | |
| SCHEMBL8600956 | 0.79 | PTAFR (0.40) | PTAFRACE2AKR1C3AKR1C2CYP11B1 | |
| SCHEMBL8597878 | 0.78 | PTAFR (0.36) | PTAFRCYP19A1CYP2C9CNR1CNR2 | |
| SCHEMBL8602905 | 0.77 | PTAFR (0.37) | PTAFRACE2CNR1CNR2 | |
| SCHEMBL8597214 | 0.76 | CYSLTR2 (0.34) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5779934-A | FLUORINATING AN ALCOHOL DERIVATIVE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1998-07-14 | — | — | US | disclosed |