Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTAFR | P25105 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 4/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.32 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.32 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8597214 | 0.83 | CYSLTR2 (0.34) | SIGMAR1MEN1POLBMAPTKMT2A | |
| SCHEMBL8598821 | 0.82 | LTA4H (0.35) | SIGMAR1AKR1C3AKR1C2HDAC1HDAC8 | |
| SCHEMBL7558904 | 0.81 | HRH3 (0.36) | SIGMAR1GRIN2DGRIN2AGRIN2BGRIN2C | |
| SCHEMBL8600416 | 0.81 | PTAFR (0.36) | PTAFR | |
| SCHEMBL8599334 | 0.80 | PTAFR (0.46) | PTAFRAKR1C3AKR1C2CNR2CNR1 | |
| SCHEMBL8601066 | 0.79 | HDAC1 (0.36) | AKR1C3AKR1C2HDAC1HDAC8 | |
| SCHEMBL8603247 | 0.79 | GRIN2D (0.39) | SIGMAR1HDAC1HDAC8CNR2GABRA1 | |
| SCHEMBL7553151 | 0.78 | PTGS2 (0.38) | SIGMAR1CNR2GABRA1GABRB2ALOX5 | |
| SCHEMBL8596601 | 0.78 | AKR1C3 (0.32) | PTAFRAKR1C3AKR1C2 | |
| SCHEMBL8601852 | 0.78 | FFAR4 (0.39) | GRIN2DGRIN2AGRIN2BGRIN2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5779934-A | FLUORINATING AN ALCOHOL DERIVATIVE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1998-07-14 | — | — | US | disclosed |