Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 10/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 10/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | PTAFR | P25105 | 2/20 | 0.37 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8602554 | 0.89 | LTA4H (0.36) | POLBLTA4HAAK1 | |
| SCHEMBL8600391 | 0.87 | PTAFR (0.40) | CYP11B1CYP11B2CYP19A1PTAFR | |
| SCHEMBL8599334 | 0.83 | PTAFR (0.46) | CYP11B1CYP11B2CYP19A1PTAFR | |
| SCHEMBL8603103 | 0.81 | PTAFR (0.43) | PTAFR | |
| SCHEMBL8598821 | 0.81 | LTA4H (0.35) | LTA4H | |
| SCHEMBL8597829 | 0.81 | CYP11B1 (0.38) | CYP11B1CYP11B2CYP19A1POLBAAK1 | |
| SCHEMBL8601450 | 0.81 | CYP11B1 (0.41) | CYP11B1CYP11B2CYP19A1POLBPTAFR | |
| SCHEMBL8596673 | 0.81 | FGFR4 (0.35) | LTA4H | |
| SCHEMBL8599817 | 0.80 | PORCN (0.34) | CYP19A1POLBLTA4HPTAFR | |
| SCHEMBL8601305 | 0.80 | PDE4A (0.34) | POLBLTA4HPTAFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5779934-A | FLUORINATING AN ALCOHOL DERIVATIVE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1998-07-14 | — | — | US | disclosed |