Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.46 |
| ▸ | CLK1 | P49759 | 4/20 | 0.46 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.46 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.41 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.41 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.40 |
| ▸ | TUBB | P07437 | 1/20 | 0.40 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.40 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9623048 | 0.87 | CLK1 (0.60) | CA2DYRK1ACLK1DYRK1BBACE1 | |
| SCHEMBL914782 | 0.80 | BCL2L1 (0.54) | CA2DYRK1ACLK1DYRK1BCHRNA7 | |
| SCHEMBL13709512 | 0.79 | F9 (0.56) | CA2DYRK1ACLK1DYRK1BCHRNA7 | |
| SCHEMBL31207841 | 0.79 | HDAC1 (0.56) | CA2DYRK1ACLK1DYRK1BCHRNA7 | |
| SCHEMBL29020102 | 0.79 | BCL2L1 (0.53) | CA2DYRK1ACLK1DYRK1BCHRNA7 | |
| SCHEMBL1098993 | 0.79 | HDAC1 (0.56) | CA2DYRK1ACLK1DYRK1BCHRNA7 | |
| SCHEMBL30298109 | 0.78 | CLK1 (0.48) | CA2DYRK1ACLK1DYRK1BCHRNA7 | |
| Potassium Ion SCHEMBL25233840 | 0.78 | CLK1 (0.50) | CA2DYRK1ACLK1DYRK1BCHRNA7 | |
| SCHEMBL22590860 | 0.77 | HDAC1 (0.60) | DYRK1ACLK1DYRK1BCHRNA7CYP1A2 | |
| SCHEMBL5542989 | 0.75 | CA2 (0.54) | CA2DYRK1ACYP1A2CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641791-B1 | NOVEL BENZOTHIOPHENE DERIVATIVE | TEIKOKU HORMONE MFG CO LTD (JP) | 1998-01-28 | — | — | EP | disclosed |
| US-5472962-A | Antiestrogenic agents | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 1995-12-05 | — | — | US | disclosed |
| EP-0641791-A1 | NOVEL BENZOTHIOPHENE DERIVATIVE | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 1995-03-08 | — | — | EP | disclosed |