Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 3/20 | 0.44 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8004235 | 1.00 | KCNA5 (0.44) | KCNA5KCNE1MEN1KMT2AKDM4E | |
| SCHEMBL8598551 | 1.00 | KCNA5 (0.44) | KCNA5KCNE1MEN1KMT2AKDM4E | |
| SCHEMBL22961730 | 0.84 | KCNA5 (0.44) | KCNA5KCNE1MEN1KMT2AKDM4E | |
| SCHEMBL6370490 | 0.84 | KCNA5 (0.44) | KCNA5KCNE1MEN1KMT2AKDM4E | |
| SCHEMBL9843699 | 0.83 | KCNA5 (0.46) | KCNA5KCNE1MEN1KMT2AKDM4E | |
| SCHEMBL6989805 | 0.79 | KMT2A (0.44) | KCNA5KCNE1MEN1KMT2AKDM4E | |
| SCHEMBL23109247 | 0.78 | KCNA5 (0.47) | KCNA5KCNE1MEN1KMT2AKDM4E | |
| SCHEMBL6182773 | 0.78 | KCNA5 (0.47) | KCNA5KCNE1MEN1KMT2AKDM4E | |
| SCHEMBL6850515 | 0.78 | KCNA5 (0.47) | KCNA5KCNE1MEN1KMT2AKDM4E | |
| SCHEMBL19332957 | 0.78 | KCNA5 (0.47) | KCNA5KCNE1MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0821672-A2 | PROCESS FOR PREPARING RACEMIC AND ENANTIOMERIC 1-(PYRIDYL)-2-CYCLOHEXYLETHYLAMINE | BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) | 1998-02-04 | — | — | EP | disclosed |
| WO-1996033173-A2 | PROCESS FOR PREPARING RACEMIC AND ENANTIOMERIC 1-(PYRIDYL)-2-CYCLOHEXYLETHYLAMINE | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 1996-10-24 | — | — | WO | disclosed |