Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 4/20 | 0.44 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8004235 | 0.84 | KCNA5 (0.44) | KCNA5KCNE1KDM4ETSHRALDH1A1 | |
| SCHEMBL22961730 | 0.84 | KCNA5 (0.44) | KCNA5KCNE1KDM4ETSHRALDH1A1 | |
| SCHEMBL8599511 | 0.84 | KCNA5 (0.44) | KCNA5KCNE1KDM4ETSHRALDH1A1 | |
| SCHEMBL8598551 | 0.84 | KCNA5 (0.44) | KCNA5KCNE1KDM4ETSHRALDH1A1 | |
| SCHEMBL9843699 | 0.83 | KCNA5 (0.46) | KCNA5KCNE1KDM4ETSHRALDH1A1 | |
| SCHEMBL21742302 | 0.76 | KCNA5 (0.49) | KCNA5KCNE1KDM4ETSHRALDH1A1 | |
| SCHEMBL6989805 | 0.76 | KMT2A (0.44) | KCNA5KCNE1KDM4EALDH1A1MEN1 | |
| SCHEMBL11031910 | 0.75 | CYP2C19 (0.41) | KCNA5KDM4EALDH1A1CYP1A2MEN1 | |
| SCHEMBL23109247 | 0.75 | KCNA5 (0.47) | KCNA5KCNE1KDM4ETSHRALDH1A1 | |
| SCHEMBL14835673 | 0.75 | SLC6A2 (0.40) | KCNA5KCNE1KDM4ETSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050107608-A1 | Ligands for use in catalytic processes | EIDGENOSSISCHE TECHNISCHE HOCHSCHULE ZURICH ETHZ (CH) | 2005-05-19 | — | — | US | disclosed |
| EP-1448575-A1 | LIGANDS FOR USE IN CATALYTIC PROCESSES | Eidgenössische Technische Hochschule (ETH) Zürich (CH) | 2004-08-25 | — | — | EP | disclosed |
| WO-2003048175-A1 | LIGANDS FOR USE IN CATALYTIC PROCESSES | EIDGENÖSSISCHE TECHNISCHE HOCHSCHULE ZÜRICH ETHZ (CH) | 2003-06-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050107608-A1 | Ligands for use in catalytic processes | PNKP, ITPA, PLCG2 | KCNA5 2706/4885KCNE1 3167/4885KDM4E 3430/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.