Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KCNA5 | P22460 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30982183 | 0.79 | KMT2A (0.63) | KMT2AMEN1KDM4EPKMLMNA | |
| SCHEMBL8599511 | 0.79 | KCNA5 (0.44) | KMT2AMEN1SMN1; SMN2KDM4EPKM | |
| SCHEMBL8598551 | 0.79 | KCNA5 (0.44) | KMT2AMEN1SMN1; SMN2KDM4EPKM | |
| SCHEMBL8004235 | 0.79 | KCNA5 (0.44) | KMT2AMEN1SMN1; SMN2KDM4EPKM | |
| SCHEMBL6370490 | 0.76 | KCNA5 (0.44) | KMT2AMEN1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL22961730 | 0.76 | KCNA5 (0.44) | KMT2AMEN1NPC1KDM4EPKM | |
| SCHEMBL11031910 | 0.75 | CYP2C19 (0.41) | KMT2AMEN1SMN1; SMN2KDM4EHPGD | |
| SCHEMBL17064526 | 0.75 | SLC6A2 (0.39) | KDM4EKCNA5ALDH1A1KCNE1 | |
| SCHEMBL9843699 | 0.75 | KCNA5 (0.46) | KMT2AMEN1NPC1RAB9AKDM4E | |
| SCHEMBL30982192 | 0.75 | KMT2A (0.57) | KMT2AMEN1SMN1; SMN2RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1334100-A1 | BOMBESIN RECEPTOR ANTAGONISTS | WARNER-LAMBERT COMPANY LLC (US) | 2003-08-13 | — | — | EP | disclosed |
| WO-2002040469-A1 | BOMBESIN RECEPTOR ANTAGONISTS | WARNER-LAMBERT COMPANY LLC (US) | 2002-05-23 | — | — | WO | disclosed |