SCHEMBL8599512

SCHEMBL8599512

C=CCOc1c(C=CCCCC(C)F)ccc2cc(-c3ncccn3)ccc12

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.32
ATM Q13315 1/20 0.31
ABL1 P00519 1/20 0.30
SRC P12931 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8599583 0.85 PIK3CD (0.30)
SCHEMBL8600108 0.84 MAPT (0.31) MAPTATM
SCHEMBL8603587 0.81
SCHEMBL8602518 0.81 SQOR (0.32) ATMABL1SRC
SCHEMBL8603734 0.78 PIK3CD (0.31)
SCHEMBL7560615 0.77 SRC (0.40) MAPTABL1SRC
SCHEMBL7560609 0.77 SRC (0.40) MAPTABL1SRC
SCHEMBL8599509 0.75 SRC (0.35) ABL1SRC
SCHEMBL8600215 0.75 ALOX5 (0.30)
SCHEMBL8672806 0.75 SRC (0.35) ABL1SRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5779934-A FLUORINATING AN ALCOHOL DERIVATIVE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-07-14 US disclosed