Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8602282 | 0.90 | HCAR2 (0.34) | HCAR2ALDH1A1LMNACES2ESR1 | |
| SCHEMBL8598744 | 0.89 | ALDH1A1 (0.44) | HCAR2ALDH1A1LMNACES2ESR1 | |
| SCHEMBL8597058 | 0.86 | ALDH1A1 (0.39) | ALDH1A1LMNATSHR | |
| SCHEMBL8596081 | 0.85 | ALDH1A1 (0.39) | HCAR2ALDH1A1LMNACES2ESR1 | |
| SCHEMBL8599805 | 0.85 | ALDH1A1 (0.34) | ALDH1A1LMNACES2 | |
| SCHEMBL8597930 | 0.84 | CES2 (0.42) | CES2TSHR | |
| SCHEMBL8595237 | 0.82 | HCAR2 (0.34) | HCAR2ALDH1A1LMNACES2ESR1 | |
| SCHEMBL8597067 | 0.82 | CES2 (0.45) | CES2TSHR | |
| SCHEMBL8595269 | 0.82 | CES2 (0.45) | CES2TSHR | |
| SCHEMBL8600176 | 0.82 | CES2 (0.45) | CES2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0592669-B1 | OPTICALLY ACTIVE TRIFLUOROLACTIC ACID DERIVATIVE AND LIQUID CRYSTAL COMPOSITION | CHISSO CORP (JP) | 1998-01-28 | — | — | EP | disclosed |
| US-5665270-A | Optically active trifluorolactic acid derivative and liquid crystal composition | CHISSO CORPORATION (JP) | 1997-09-09 | — | — | US | disclosed |
| EP-0592669-A1 | OPTICALLY ACTIVE TRIFLUOROLACTIC ACID DERIVATIVE AND LIQUID CRYSTAL COMPOSITION | CHISSO CORPORATION (JP) | 1994-04-20 | — | — | EP | disclosed |