Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ARG1 | P05089 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | PLG | P00747 | 1/20 | 0.34 |
| ▸ | PLAT | P00750 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.31 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8598012 | 0.90 | LMNA (0.42) | BLMARG1LMNAPLGPLAT | |
| SCHEMBL8596550 | 0.90 | LMNA (0.42) | BLMARG1LMNAPLGPLAT | |
| SCHEMBL8597733 | 0.85 | PLG (0.36) | ARG1LMNAPLGPLAT | |
| SCHEMBL8598907 | 0.84 | GSR (0.39) | ARG1LMNAPLGPLATDPP4 | |
| SCHEMBL8595707 | 0.83 | GSR (0.45) | ARG1LMNAPLGPLATDPP4 | |
| SCHEMBL8596987 | 0.82 | PLG (0.38) | ARG1LMNAPLGPLAT | |
| SCHEMBL8597484 | 0.81 | PLG (0.37) | ARG1LMNAPLGPLATDPP4 | |
| SCHEMBL8600966 | 0.81 | PTGS1 (0.37) | ARG1LMNAPLGPLAT | |
| SCHEMBL8595948 | 0.81 | ARG1 (0.38) | KMT2AARG1LMNAPLGPLAT | |
| SCHEMBL8601006 | 0.78 | SLC7A5 (0.41) | ARG1LMNAPLGPLATDPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0585130-B1 | External preparation for skin containing a depigmentation agent | SHISEIDO CO LTD (JP) | 1998-01-28 | — | — | EP | disclosed |
| US-5690914-A | TRANEXAMIC ACID DERIVATIVES FOR DEPIGMENTATION | SHISEIDO CO., LTD (JP) | 1997-11-25 | — | — | US | disclosed |
| EP-0585130-A2 | External preparation for skin containing a depigmentation agent | SHISEIDO COMPANY LIMITED (JP) | 1994-03-02 | — | — | EP | disclosed |