Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | PTAFR | P25105 | 1/20 | 0.34 |
| ▸ | PLK1 | P53350 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10532449 | 0.85 | CHRM1 (0.37) | CHRM1TSHRHTTPOLBCHRM5 | |
| SCHEMBL30010421 | 0.85 | CHRM1 (0.37) | CHRM1TSHRHTTPOLBCHRM5 | |
| SCHEMBL6724624 | 0.85 | CHRM1 (0.37) | CHRM1TSHRHTTPOLBCHRM5 | |
| SCHEMBL8600207 | 0.83 | RORC (0.43) | CHRM1TSHRHTTPOLBCHRM5 | |
| SCHEMBL8602365 | 0.81 | CHRM1 (0.47) | CHRM1TSHRHTTPOLBCHRM5 | |
| SCHEMBL8602191 | 0.80 | CHRM1 (0.37) | CHRM1TSHRHTTPOLBCHRM5 | |
| SCHEMBL8878855 | 0.80 | CHRM1 (0.41) | CHRM1TSHRHTTPOLBCHRM5 | |
| SCHEMBL29901589 | 0.79 | CHRM1 (0.43) | CHRM1TSHRHTTCHRM5CHRM3 | |
| SCHEMBL8599840 | 0.79 | CHRM1 (0.51) | CHRM1POLBCHRM5CHRM3 | |
| SCHEMBL10431134 | 0.79 | HTT (0.47) | CHRM1TSHRHTTPOLBPLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113200985-B | Pteridinone compound and preparation method and application thereof | 南开大学 | 2022-09-09 | — | — | CN | disclosed |
| EP-0626370-B1 | Process for producing aromatic isothiocyanate derivatives | SUMITOMO CHEMICAL CO (JP) | 1998-02-11 | — | — | EP | disclosed |
| EP-0626370-A1 | Process for producing aromatic isothiocyanate derivatives | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1994-11-30 | — | — | EP | disclosed |